node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Abat | Acss1 | ENSRNOP00000003633 | ENSRNOP00000009627 | 4-aminobutyrate aminotransferase, brain isoform; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetyl-coenzyme A synthetase. | 0.829 |
Abat | Acss2 | ENSRNOP00000003633 | ENSRNOP00000059987 | 4-aminobutyrate aminotransferase, brain isoform; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acyl-CoA synthetase short-chain family member 2 (Predicted). | 0.832 |
Abat | Aldh2 | ENSRNOP00000003633 | ENSRNOP00000001816 | 4-aminobutyrate aminotransferase, brain isoform; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aldehyde dehydrogenase, mitochondrial. | 0.949 |
Abat | Hadh | ENSRNOP00000003633 | ENSRNOP00000014658 | 4-aminobutyrate aminotransferase, brain isoform; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3- hydroxybutyryl-CoA; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.923 |
Abat | Hibadh | ENSRNOP00000003633 | ENSRNOP00000011069 | 4-aminobutyrate aminotransferase, brain isoform; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 3-hydroxyisobutyrate dehydrogenase, mitochondrial. | 0.947 |
Abat | Maob | ENSRNOP00000003633 | ENSRNOP00000043466 | 4-aminobutyrate aminotransferase, brain isoform; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. | 0.489 |
Acss1 | Abat | ENSRNOP00000009627 | ENSRNOP00000003633 | Acetyl-coenzyme A synthetase. | 4-aminobutyrate aminotransferase, brain isoform; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.829 |
Acss1 | Acss2 | ENSRNOP00000009627 | ENSRNOP00000059987 | Acetyl-coenzyme A synthetase. | Acyl-CoA synthetase short-chain family member 2 (Predicted). | 0.910 |
Acss1 | Aldh2 | ENSRNOP00000009627 | ENSRNOP00000001816 | Acetyl-coenzyme A synthetase. | Aldehyde dehydrogenase, mitochondrial. | 0.954 |
Acss1 | Hadh | ENSRNOP00000009627 | ENSRNOP00000014658 | Acetyl-coenzyme A synthetase. | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3- hydroxybutyryl-CoA; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.921 |
Acss1 | Hibadh | ENSRNOP00000009627 | ENSRNOP00000011069 | Acetyl-coenzyme A synthetase. | 3-hydroxyisobutyrate dehydrogenase, mitochondrial. | 0.828 |
Acss2 | Abat | ENSRNOP00000059987 | ENSRNOP00000003633 | Acyl-CoA synthetase short-chain family member 2 (Predicted). | 4-aminobutyrate aminotransferase, brain isoform; Catalyzes the conversion of gamma-aminobutyrate and L-beta- aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.832 |
Acss2 | Acss1 | ENSRNOP00000059987 | ENSRNOP00000009627 | Acyl-CoA synthetase short-chain family member 2 (Predicted). | Acetyl-coenzyme A synthetase. | 0.910 |
Acss2 | Aldh2 | ENSRNOP00000059987 | ENSRNOP00000001816 | Acyl-CoA synthetase short-chain family member 2 (Predicted). | Aldehyde dehydrogenase, mitochondrial. | 0.958 |
Acss2 | Hadh | ENSRNOP00000059987 | ENSRNOP00000014658 | Acyl-CoA synthetase short-chain family member 2 (Predicted). | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3- hydroxybutyryl-CoA; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.918 |
Acss2 | Hibadh | ENSRNOP00000059987 | ENSRNOP00000011069 | Acyl-CoA synthetase short-chain family member 2 (Predicted). | 3-hydroxyisobutyrate dehydrogenase, mitochondrial. | 0.829 |
Adh4 | Adh7 | ENSRNOP00000069857 | ENSRNOP00000015870 | Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | All-trans-retinol dehydrogenase [NAD(+)] ADH7; Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, aldehyde and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency [...] | 0.916 |
Adh4 | Aldh2 | ENSRNOP00000069857 | ENSRNOP00000001816 | Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Aldehyde dehydrogenase, mitochondrial. | 0.978 |
Adh4 | Maoa | ENSRNOP00000069857 | ENSRNOP00000063784 | Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. | 0.929 |
Adh4 | Maob | ENSRNOP00000069857 | ENSRNOP00000043466 | Alcohol dehydrogenase class-3; Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. | 0.925 |