Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ccdc150 | Iqck | ENSRNOP00000017859 | ENSRNOP00000051971 | Coiled-coil domain-containing 150. | IQ motif-containing K. | 0.475 |
| Ccdc150 | Slc49a4 | ENSRNOP00000017859 | ENSRNOP00000003048 | Coiled-coil domain-containing 150. | Solute carrier family 49 member 4; Electrogenic metabolite transporter. | 0.478 |
| Epas1 | Hif1a | ENSRNOP00000075020 | ENSRNOP00000042230 | Endothelial PAS domain-containing protein 1; Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase e [...] | Hypoxia-inducible factor 1-alpha; Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Heterodimerizes with ARNT; heterodimer binds to core DNA sequenc [...] | 0.997 |
| Epas1 | Slc49a4 | ENSRNOP00000075020 | ENSRNOP00000003048 | Endothelial PAS domain-containing protein 1; Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase e [...] | Solute carrier family 49 member 4; Electrogenic metabolite transporter. | 0.566 |
| Epas1 | Vhl | ENSRNOP00000075020 | ENSRNOP00000013727 | Endothelial PAS domain-containing protein 1; Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase e [...] | Von Hippel-Lindau disease tumor suppressor; Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2 (By similarity). | 0.998 |
| Gak | Slc49a4 | ENSRNOP00000000064 | ENSRNOP00000003048 | Cyclin-G-associated kinase; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1 (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | Solute carrier family 49 member 4; Electrogenic metabolite transporter. | 0.494 |
| Hif1a | Epas1 | ENSRNOP00000042230 | ENSRNOP00000075020 | Hypoxia-inducible factor 1-alpha; Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Heterodimerizes with ARNT; heterodimer binds to core DNA sequenc [...] | Endothelial PAS domain-containing protein 1; Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase e [...] | 0.997 |
| Hif1a | Slc49a4 | ENSRNOP00000042230 | ENSRNOP00000003048 | Hypoxia-inducible factor 1-alpha; Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Heterodimerizes with ARNT; heterodimer binds to core DNA sequenc [...] | Solute carrier family 49 member 4; Electrogenic metabolite transporter. | 0.556 |
| Hif1a | Vhl | ENSRNOP00000042230 | ENSRNOP00000013727 | Hypoxia-inducible factor 1-alpha; Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Heterodimerizes with ARNT; heterodimer binds to core DNA sequenc [...] | Von Hippel-Lindau disease tumor suppressor; Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2 (By similarity). | 0.999 |
| Iqck | Ccdc150 | ENSRNOP00000051971 | ENSRNOP00000017859 | IQ motif-containing K. | Coiled-coil domain-containing 150. | 0.475 |
| Iqck | Slc49a4 | ENSRNOP00000051971 | ENSRNOP00000003048 | IQ motif-containing K. | Solute carrier family 49 member 4; Electrogenic metabolite transporter. | 0.471 |
| Rcbtb2 | Slc49a4 | ENSRNOP00000070018 | ENSRNOP00000003048 | RCC1 and BTB domain-containing protein 2. | Solute carrier family 49 member 4; Electrogenic metabolite transporter. | 0.499 |
| Slc35b3 | Slc49a4 | ENSRNOP00000021670 | ENSRNOP00000003048 | Solute carrier family 35 member B3. | Solute carrier family 49 member 4; Electrogenic metabolite transporter. | 0.441 |
| Slc36a1 | Slc38a7 | ENSRNOP00000074412 | ENSRNOP00000058216 | Proton-coupled amino acid transporter 1; Neutral amino acid/proton symporter. Probably involved in the efflux of lysosomal proteolysis products such as L-proline, L-alanine and glycine from the cell. May play a role in specifying sites for exocytosis in neurons. | Putative sodium-coupled neutral amino acid transporter 7; Mediates sodium-dependent transport of amino acids, preferentially L-glutamine; Belongs to the amino acid/polyamine transporter 2 family. | 0.667 |
| Slc36a1 | Slc49a4 | ENSRNOP00000074412 | ENSRNOP00000003048 | Proton-coupled amino acid transporter 1; Neutral amino acid/proton symporter. Probably involved in the efflux of lysosomal proteolysis products such as L-proline, L-alanine and glycine from the cell. May play a role in specifying sites for exocytosis in neurons. | Solute carrier family 49 member 4; Electrogenic metabolite transporter. | 0.443 |
| Slc38a7 | Slc36a1 | ENSRNOP00000058216 | ENSRNOP00000074412 | Putative sodium-coupled neutral amino acid transporter 7; Mediates sodium-dependent transport of amino acids, preferentially L-glutamine; Belongs to the amino acid/polyamine transporter 2 family. | Proton-coupled amino acid transporter 1; Neutral amino acid/proton symporter. Probably involved in the efflux of lysosomal proteolysis products such as L-proline, L-alanine and glycine from the cell. May play a role in specifying sites for exocytosis in neurons. | 0.667 |
| Slc38a7 | Slc49a4 | ENSRNOP00000058216 | ENSRNOP00000003048 | Putative sodium-coupled neutral amino acid transporter 7; Mediates sodium-dependent transport of amino acids, preferentially L-glutamine; Belongs to the amino acid/polyamine transporter 2 family. | Solute carrier family 49 member 4; Electrogenic metabolite transporter. | 0.505 |
| Slc49a4 | Ccdc150 | ENSRNOP00000003048 | ENSRNOP00000017859 | Solute carrier family 49 member 4; Electrogenic metabolite transporter. | Coiled-coil domain-containing 150. | 0.478 |
| Slc49a4 | Epas1 | ENSRNOP00000003048 | ENSRNOP00000075020 | Solute carrier family 49 member 4; Electrogenic metabolite transporter. | Endothelial PAS domain-containing protein 1; Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase e [...] | 0.566 |
| Slc49a4 | Gak | ENSRNOP00000003048 | ENSRNOP00000000064 | Solute carrier family 49 member 4; Electrogenic metabolite transporter. | Cyclin-G-associated kinase; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1 (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.494 |
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