node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Itga3 | Itga5 | ENSRNOP00000034608 | ENSRNOP00000071805 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | 0.954 |
Itga3 | Itga6 | ENSRNOP00000034608 | ENSRNOP00000002075 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Integrin, alpha 6, isoform CRA_a; Belongs to the integrin alpha chain family. | 0.947 |
Itga3 | Itga7 | ENSRNOP00000034608 | ENSRNOP00000028983 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Integrin alpha-7 70 kDa form; Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. Involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells (By similarity). Acts as Schwann cell receptor [...] | 0.908 |
Itga3 | Itga9 | ENSRNOP00000034608 | ENSRNOP00000015113 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Integrin subunit alpha 9; Belongs to the integrin alpha chain family. | 0.914 |
Itga3 | Itgb1 | ENSRNOP00000034608 | ENSRNOP00000014785 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.997 |
Itga3 | Itgb3 | ENSRNOP00000034608 | ENSRNOP00000067271 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Integrin beta-3; Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIB/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIB/beta-3 and alpha- V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIB/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A- G-D-V in fibrinogen gamma chain. Following ac [...] | 0.982 |
Itga3 | Lyn | ENSRNOP00000034608 | ENSRNOP00000011130 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Tyrosine-protein kinase Lyn; Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. Functions primarily as negative regulator, but can also function as activator, depending on the context. Required for the initiation of the B-cell response, but also for its down-regulation and termination. Plays an important role in the regulation of B-c [...] | 0.904 |
Itga3 | Plp1 | ENSRNOP00000034608 | ENSRNOP00000003283 | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. | 0.903 |
Itga5 | Itga3 | ENSRNOP00000071805 | ENSRNOP00000034608 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | 0.954 |
Itga5 | Itga6 | ENSRNOP00000071805 | ENSRNOP00000002075 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Integrin, alpha 6, isoform CRA_a; Belongs to the integrin alpha chain family. | 0.949 |
Itga5 | Itga7 | ENSRNOP00000071805 | ENSRNOP00000028983 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Integrin alpha-7 70 kDa form; Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. Involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells (By similarity). Acts as Schwann cell receptor [...] | 0.922 |
Itga5 | Itga9 | ENSRNOP00000071805 | ENSRNOP00000015113 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Integrin subunit alpha 9; Belongs to the integrin alpha chain family. | 0.943 |
Itga5 | Itgb1 | ENSRNOP00000071805 | ENSRNOP00000014785 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.999 |
Itga5 | Itgb3 | ENSRNOP00000071805 | ENSRNOP00000067271 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Integrin beta-3; Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIB/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIB/beta-3 and alpha- V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIB/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A- G-D-V in fibrinogen gamma chain. Following ac [...] | 0.996 |
Itga5 | Lyn | ENSRNOP00000071805 | ENSRNOP00000011130 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Tyrosine-protein kinase Lyn; Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. Functions primarily as negative regulator, but can also function as activator, depending on the context. Required for the initiation of the B-cell response, but also for its down-regulation and termination. Plays an important role in the regulation of B-c [...] | 0.913 |
Itga5 | Plp1 | ENSRNOP00000071805 | ENSRNOP00000003283 | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. | 0.906 |
Itga6 | Itga3 | ENSRNOP00000002075 | ENSRNOP00000034608 | Integrin, alpha 6, isoform CRA_a; Belongs to the integrin alpha chain family. | Integrin alpha 3 variant B; Belongs to the integrin alpha chain family. | 0.947 |
Itga6 | Itga5 | ENSRNOP00000002075 | ENSRNOP00000071805 | Integrin, alpha 6, isoform CRA_a; Belongs to the integrin alpha chain family. | Integrin alpha 5 (Mapped); Belongs to the integrin alpha chain family. | 0.949 |
Itga6 | Itga7 | ENSRNOP00000002075 | ENSRNOP00000028983 | Integrin, alpha 6, isoform CRA_a; Belongs to the integrin alpha chain family. | Integrin alpha-7 70 kDa form; Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. Involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells (By similarity). Acts as Schwann cell receptor [...] | 0.908 |
Itga6 | Itga9 | ENSRNOP00000002075 | ENSRNOP00000015113 | Integrin, alpha 6, isoform CRA_a; Belongs to the integrin alpha chain family. | Integrin subunit alpha 9; Belongs to the integrin alpha chain family. | 0.914 |