node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Egr2 | Gdap1 | ENSRNOP00000000792 | ENSRNOP00000007994 | E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity). | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | 0.452 |
Egr2 | Gjb1 | ENSRNOP00000000792 | ENSRNOP00000068248 | E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity). | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.680 |
Egr2 | Mpz | ENSRNOP00000000792 | ENSRNOP00000004279 | E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity). | Myelin protein P0; Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction. | 0.780 |
Egr2 | Nrg1 | ENSRNOP00000000792 | ENSRNOP00000072731 | E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity). | Pro-neuregulin-1, membrane-bound isoform; Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gla [...] | 0.663 |
Egr2 | Plp1 | ENSRNOP00000000792 | ENSRNOP00000003283 | E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity). | Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. | 0.470 |
Egr2 | Pmp2 | ENSRNOP00000000792 | ENSRNOP00000036672 | E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity). | Peripheral myelin protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | 0.509 |
Egr2 | Prx | ENSRNOP00000000792 | ENSRNOP00000024771 | E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity). | Periaxin; Scaffolding protein that functions as part of a dystroglycan complex in Schwann cells, and as part of EZR and AHNAK-containing complexes in eye lens fiber cells. Required for the maintenance of the peripheral myelin sheath that is essential for normal transmission of nerve impulses and normal perception of sensory stimuli. Required for normal transport of MBP mRNA from the perinuclear to the paranodal regions. Required for normal remyelination after nerve injury. Required for normal elongation of Schwann cells and normal length of the internodes between the nodes of Ranvier. [...] | 0.755 |
Egr2 | Sh3tc2 | ENSRNOP00000000792 | ENSRNOP00000026174 | E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity). | SH3 domain and tetratricopeptide repeats 2. | 0.516 |
Egr2 | Sox10 | ENSRNOP00000000792 | ENSRNOP00000015283 | E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity). | Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity). | 0.979 |
Gdap1 | Egr2 | ENSRNOP00000007994 | ENSRNOP00000000792 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity). | 0.452 |
Gdap1 | Gjb1 | ENSRNOP00000007994 | ENSRNOP00000068248 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.564 |
Gdap1 | Mpz | ENSRNOP00000007994 | ENSRNOP00000004279 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | Myelin protein P0; Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction. | 0.662 |
Gdap1 | Pmp2 | ENSRNOP00000007994 | ENSRNOP00000036672 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | Peripheral myelin protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | 0.479 |
Gdap1 | Sh3tc2 | ENSRNOP00000007994 | ENSRNOP00000026174 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | SH3 domain and tetratricopeptide repeats 2. | 0.835 |
Gjb1 | Egr2 | ENSRNOP00000068248 | ENSRNOP00000000792 | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | E3 SUMO-protein ligase EGR2; Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2 (By similarity). | 0.680 |
Gjb1 | Gdap1 | ENSRNOP00000068248 | ENSRNOP00000007994 | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | 0.564 |
Gjb1 | Mpz | ENSRNOP00000068248 | ENSRNOP00000004279 | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Myelin protein P0; Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction. | 0.701 |
Gjb1 | Mpzl1 | ENSRNOP00000068248 | ENSRNOP00000004376 | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Myelin protein zero-like protein 1; Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. May be involved in regulation of integrin-mediated cell motility (By similarity); Belongs to the myelin P0 protein family. | 0.424 |
Gjb1 | Plp1 | ENSRNOP00000068248 | ENSRNOP00000003283 | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. | 0.481 |
Gjb1 | Pmp2 | ENSRNOP00000068248 | ENSRNOP00000036672 | Gap junction beta-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Peripheral myelin protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. | 0.452 |