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Dpys Dpys Dpyd Dpyd Upb1 Upb1 Umps Umps Dhodh Dhodh Cps1 Cps1 Gart Gart Cad Cad Gpr143 Gpr143 Tmem116 Tmem116 Golt1a Golt1a
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query proteins and first shell of interactors
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second shell of interactors
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Predicted Interactions
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textmining
co-expression
protein homology
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DpysDihydropyrimidinase; Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. (519 aa)    
Predicted Functional Partners:
Dpyd
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity).
  
 0.910
Upb1
Beta-ureidopropionase; Catalyzes a late step in pyrimidine degradation. Converts N- carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta- aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide; Belongs to the carbon-nitrogen hydrolase superfamily. BUP family.
 
 
 0.880
Umps
Uridine monophosphate synthetase, isoform CRA_a.
  
  
 0.808
Dhodh
Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
  
 0.768
Cps1
Carbamoyl-phosphate synthase [ammonia], mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.
  
 0.733
Gart
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
  
  
 0.699
Cad
Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.
  
0.678
Gpr143
G protein-coupled receptor 143 (Predicted).
  
 0.674
Tmem116
Transmembrane protein 116.
  
 0.674
Golt1a
Similar to RIKEN cDNA 0610012C01 (Predicted), isoform CRA_a.
  
 
 0.662
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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