node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cttnbp2 | Cttnbp2nl | ENSRNOP00000072761 | ENSRNOP00000019680 | Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance. | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | 0.942 |
Cttnbp2 | Mob4 | ENSRNOP00000072761 | ENSRNOP00000020536 | Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance. | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | 0.907 |
Cttnbp2 | Pdcd10 | ENSRNOP00000072761 | ENSRNOP00000013585 | Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance. | Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. | 0.950 |
Cttnbp2 | Sike1 | ENSRNOP00000072761 | ENSRNOP00000024270 | Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance. | Suppressor of IKBKE 1; Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3- mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity). | 0.511 |
Cttnbp2 | Stk24 | ENSRNOP00000072761 | ENSRNOP00000031981 | Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance. | Serine/threonine-protein kinase 24 12 kDa subunit; Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr [...] | 0.958 |
Cttnbp2 | Stk25 | ENSRNOP00000072761 | ENSRNOP00000024487 | Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance. | Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a. | 0.947 |
Cttnbp2 | Strip1 | ENSRNOP00000072761 | ENSRNOP00000025036 | Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance. | Striatin-interacting protein 1. | 0.984 |
Cttnbp2 | Strn | ENSRNOP00000072761 | ENSRNOP00000006527 | Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance. | Striatin; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | 0.975 |
Cttnbp2 | Strn3 | ENSRNOP00000072761 | ENSRNOP00000074395 | Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance. | Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein (By similarity); Belongs to the WD repeat striatin family. | 0.986 |
Cttnbp2 | Strn4 | ENSRNOP00000072761 | ENSRNOP00000021976 | Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance. | Striatin 4. | 0.952 |
Cttnbp2nl | Cttnbp2 | ENSRNOP00000019680 | ENSRNOP00000072761 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Cortactin-binding protein 2; Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance. | 0.942 |
Cttnbp2nl | Mob4 | ENSRNOP00000019680 | ENSRNOP00000020536 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions. | 0.970 |
Cttnbp2nl | Pdcd10 | ENSRNOP00000019680 | ENSRNOP00000013585 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. | 0.970 |
Cttnbp2nl | Sike1 | ENSRNOP00000019680 | ENSRNOP00000024270 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Suppressor of IKBKE 1; Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3- mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity). | 0.682 |
Cttnbp2nl | Stk24 | ENSRNOP00000019680 | ENSRNOP00000031981 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Serine/threonine-protein kinase 24 12 kDa subunit; Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr [...] | 0.975 |
Cttnbp2nl | Stk25 | ENSRNOP00000019680 | ENSRNOP00000024487 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a. | 0.950 |
Cttnbp2nl | Strip1 | ENSRNOP00000019680 | ENSRNOP00000025036 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Striatin-interacting protein 1. | 0.987 |
Cttnbp2nl | Strn | ENSRNOP00000019680 | ENSRNOP00000006527 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Striatin; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | 0.980 |
Cttnbp2nl | Strn3 | ENSRNOP00000019680 | ENSRNOP00000074395 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein (By similarity); Belongs to the WD repeat striatin family. | 0.990 |
Cttnbp2nl | Strn4 | ENSRNOP00000019680 | ENSRNOP00000021976 | CTTNBP2 N-terminal like (Predicted), isoform CRA_a. | Striatin 4. | 0.982 |