Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Brca2 | Spo11 | ENSRNOP00000001475 | ENSRNOP00000075147 | Breast cancer type 2 susceptibility protein homolog; Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51- ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint acti [...] | SPO11, initiator of meiotic double stranded breaks. | 0.539 |
| Brca2 | Sycp3 | ENSRNOP00000001475 | ENSRNOP00000007088 | Breast cancer type 2 susceptibility protein homolog; Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51- ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint acti [...] | Synaptonemal complex protein 3; Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells. Required for normal meiosis during spermatogenesis and male fertility. Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2. Belongs to the XLR/SYCP3 family. | 0.930 |
| Dazl | Hormad2 | ENSRNOP00000070802 | ENSRNOP00000068948 | Deleted in azoospermia-like. | HORMA domain-containing 2. | 0.503 |
| Dazl | Rec8 | ENSRNOP00000070802 | ENSRNOP00000072690 | Deleted in azoospermia-like. | Meiotic recombination protein REC8 homolog; Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity); Belongs to the rad21 family. | 0.643 |
| Dazl | Spo11 | ENSRNOP00000070802 | ENSRNOP00000075147 | Deleted in azoospermia-like. | SPO11, initiator of meiotic double stranded breaks. | 0.549 |
| Dazl | Stra8 | ENSRNOP00000070802 | ENSRNOP00000014093 | Deleted in azoospermia-like. | Stimulated by retinoic acid 8. | 0.860 |
| Dazl | Syce1 | ENSRNOP00000070802 | ENSRNOP00000035554 | Deleted in azoospermia-like. | Synaptonemal complex central element protein 1; Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination. | 0.424 |
| Dazl | Sycp1 | ENSRNOP00000070802 | ENSRNOP00000023333 | Deleted in azoospermia-like. | Synaptonemal complex protein 1; Major component of the transverse filaments of synaptonemal complexes, formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. | 0.722 |
| Dazl | Sycp3 | ENSRNOP00000070802 | ENSRNOP00000007088 | Deleted in azoospermia-like. | Synaptonemal complex protein 3; Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells. Required for normal meiosis during spermatogenesis and male fertility. Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2. Belongs to the XLR/SYCP3 family. | 0.813 |
| Hormad2 | Dazl | ENSRNOP00000068948 | ENSRNOP00000070802 | HORMA domain-containing 2. | Deleted in azoospermia-like. | 0.503 |
| Hormad2 | Rec8 | ENSRNOP00000068948 | ENSRNOP00000072690 | HORMA domain-containing 2. | Meiotic recombination protein REC8 homolog; Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity); Belongs to the rad21 family. | 0.773 |
| Hormad2 | Rnf212 | ENSRNOP00000068948 | ENSRNOP00000070745 | HORMA domain-containing 2. | Ring finger protein 212. | 0.504 |
| Hormad2 | Spo11 | ENSRNOP00000068948 | ENSRNOP00000075147 | HORMA domain-containing 2. | SPO11, initiator of meiotic double stranded breaks. | 0.861 |
| Hormad2 | Stra8 | ENSRNOP00000068948 | ENSRNOP00000014093 | HORMA domain-containing 2. | Stimulated by retinoic acid 8. | 0.444 |
| Hormad2 | Syce1 | ENSRNOP00000068948 | ENSRNOP00000035554 | HORMA domain-containing 2. | Synaptonemal complex central element protein 1; Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination. | 0.773 |
| Hormad2 | Syce2 | ENSRNOP00000068948 | ENSRNOP00000004404 | HORMA domain-containing 2. | Synaptonemal complex central element protein 2. | 0.761 |
| Hormad2 | Sycp1 | ENSRNOP00000068948 | ENSRNOP00000023333 | HORMA domain-containing 2. | Synaptonemal complex protein 1; Major component of the transverse filaments of synaptonemal complexes, formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. | 0.829 |
| Hormad2 | Sycp3 | ENSRNOP00000068948 | ENSRNOP00000007088 | HORMA domain-containing 2. | Synaptonemal complex protein 3; Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells. Required for normal meiosis during spermatogenesis and male fertility. Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2. Belongs to the XLR/SYCP3 family. | 0.959 |
| Rec8 | Dazl | ENSRNOP00000072690 | ENSRNOP00000070802 | Meiotic recombination protein REC8 homolog; Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity); Belongs to the rad21 family. | Deleted in azoospermia-like. | 0.643 |
| Rec8 | Hormad2 | ENSRNOP00000072690 | ENSRNOP00000068948 | Meiotic recombination protein REC8 homolog; Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity); Belongs to the rad21 family. | HORMA domain-containing 2. | 0.773 |
page 1 of 5