node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aprt | Gmps | ENSRNOP00000061449 | ENSRNOP00000072183 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase [glutamine-hydrolyzing]. | 0.991 |
Aprt | Guk1 | ENSRNOP00000061449 | ENSRNOP00000003926 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase 1, isoform CRA_a. | 0.966 |
Aprt | Itpa | ENSRNOP00000061449 | ENSRNOP00000028838 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.985 |
Aprt | LOC103689983 | ENSRNOP00000061449 | ENSRNOP00000043388 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | 0.979 |
Aprt | Pde6a | ENSRNOP00000061449 | ENSRNOP00000024171 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphodiesterase. | 0.908 |
Aprt | Pde6c | ENSRNOP00000061449 | ENSRNOP00000022317 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphodiesterase. | 0.907 |
Aprt | Pde6h | ENSRNOP00000061449 | ENSRNOP00000007905 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G- protein-mediated phototransduction in vertebrate rods and cones (By similarity); Belongs to the rod/cone cGMP-PDE gamma subunit family. | 0.900 |
Gmps | Aprt | ENSRNOP00000072183 | ENSRNOP00000061449 | GMP synthase [glutamine-hydrolyzing]. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.991 |
Gmps | Guk1 | ENSRNOP00000072183 | ENSRNOP00000003926 | GMP synthase [glutamine-hydrolyzing]. | Guanylate kinase 1, isoform CRA_a. | 0.973 |
Gmps | Itpa | ENSRNOP00000072183 | ENSRNOP00000028838 | GMP synthase [glutamine-hydrolyzing]. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.960 |
Gmps | LOC103689983 | ENSRNOP00000072183 | ENSRNOP00000043388 | GMP synthase [glutamine-hydrolyzing]. | Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). | 0.943 |
Gmps | Pde6a | ENSRNOP00000072183 | ENSRNOP00000024171 | GMP synthase [glutamine-hydrolyzing]. | Phosphodiesterase. | 0.902 |
Gmps | Pde6c | ENSRNOP00000072183 | ENSRNOP00000022317 | GMP synthase [glutamine-hydrolyzing]. | Phosphodiesterase. | 0.901 |
Gmps | Pde6h | ENSRNOP00000072183 | ENSRNOP00000007905 | GMP synthase [glutamine-hydrolyzing]. | Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G- protein-mediated phototransduction in vertebrate rods and cones (By similarity); Belongs to the rod/cone cGMP-PDE gamma subunit family. | 0.900 |
Gnat1 | Gnat2 | ENSRNOP00000023791 | ENSRNOP00000026237 | G protein subunit alpha transducin 1. | Guanine nucleotide binding protein, alpha transducing 2 (Predicted), isoform CRA_b. | 0.952 |
Gnat1 | Gucy2d | ENSRNOP00000023791 | ENSRNOP00000020513 | G protein subunit alpha transducin 1. | Guanylate cyclase 2D; Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity). | 0.476 |
Gnat1 | Guk1 | ENSRNOP00000023791 | ENSRNOP00000003926 | G protein subunit alpha transducin 1. | Guanylate kinase 1, isoform CRA_a. | 0.514 |
Gnat1 | Pde6a | ENSRNOP00000023791 | ENSRNOP00000024171 | G protein subunit alpha transducin 1. | Phosphodiesterase. | 0.980 |
Gnat1 | Pde6c | ENSRNOP00000023791 | ENSRNOP00000022317 | G protein subunit alpha transducin 1. | Phosphodiesterase. | 0.740 |
Gnat1 | Pde6h | ENSRNOP00000023791 | ENSRNOP00000007905 | G protein subunit alpha transducin 1. | Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G- protein-mediated phototransduction in vertebrate rods and cones (By similarity); Belongs to the rod/cone cGMP-PDE gamma subunit family. | 0.824 |