STRINGSTRING
Tex14 Tex14 Tex11 Tex11 Tex15 Tex15 Pdcl2 Pdcl2 Tex13c Tex13c Rbm44 Rbm44 Taf4b Taf4b Capn12 Capn12 Wdr73 Wdr73 Atf7ip Atf7ip Dmrt1 Dmrt1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Tex14Inactive serine/threonine-protein kinase TEX14; Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodie [...] (1446 aa)    
Predicted Functional Partners:
Tex11
Testis-expressed 11.
    
 
 0.613
Tex15
Testis-expressed 15, meiosis and synapsis-associated.
    
 
 0.584
Pdcl2
Phosducin-like 2.
    
 
 0.582
Tex13c
Similar to testis expressed sequence 13B.
   
 
 0.557
Rbm44
RNA-binding protein 44; Component of intercellular bridges during meiosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells. Not required for fertility (By similarity).
      
 0.546
Taf4b
TATA-box-binding protein-associated factor 4b.
    
 
 0.538
Capn12
Calpain 12; Belongs to the peptidase C2 family.
    
 
 0.533
Wdr73
Neuromedin B (Predicted), isoform CRA_d.
    
 
 0.511
Atf7ip
Activating transcription factor 7-interacting protein.
    
 
 0.510
Dmrt1
Doublesex and mab-3 related transcription factor 1.
   
  
 0.502
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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