node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cyba | Cybb | ENSRNOP00000017564 | ENSRNOP00000031063 | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. | Cytochrome b-245, beta polypeptide, isoform CRA_a. | 0.999 |
Cyba | Ncf1 | ENSRNOP00000017564 | ENSRNOP00000002028 | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | 0.999 |
Cyba | Ncf4 | ENSRNOP00000017564 | ENSRNOP00000009544 | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. | Similar to neutrophil cytosolic factor 4, isoform CRA_a. | 0.997 |
Cyba | Rac2 | ENSRNOP00000017564 | ENSRNOP00000009994 | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. | Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). | 0.999 |
Cyba | Vav1 | ENSRNOP00000017564 | ENSRNOP00000064264 | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. | Proto-oncogene vav; Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. | 0.633 |
Cybb | Cyba | ENSRNOP00000031063 | ENSRNOP00000017564 | Cytochrome b-245, beta polypeptide, isoform CRA_a. | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. | 0.999 |
Cybb | Ncf1 | ENSRNOP00000031063 | ENSRNOP00000002028 | Cytochrome b-245, beta polypeptide, isoform CRA_a. | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | 0.999 |
Cybb | Ncf4 | ENSRNOP00000031063 | ENSRNOP00000009544 | Cytochrome b-245, beta polypeptide, isoform CRA_a. | Similar to neutrophil cytosolic factor 4, isoform CRA_a. | 0.996 |
Cybb | Rac2 | ENSRNOP00000031063 | ENSRNOP00000009994 | Cytochrome b-245, beta polypeptide, isoform CRA_a. | Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). | 0.999 |
Cybb | Vav1 | ENSRNOP00000031063 | ENSRNOP00000064264 | Cytochrome b-245, beta polypeptide, isoform CRA_a. | Proto-oncogene vav; Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. | 0.652 |
Dock2 | Prex1 | ENSRNOP00000056557 | ENSRNOP00000009517 | Uncharacterized protein; Belongs to the DOCK family. | Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1. | 0.415 |
Dock2 | Rac2 | ENSRNOP00000056557 | ENSRNOP00000009994 | Uncharacterized protein; Belongs to the DOCK family. | Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). | 0.987 |
Dock2 | Vav1 | ENSRNOP00000056557 | ENSRNOP00000064264 | Uncharacterized protein; Belongs to the DOCK family. | Proto-oncogene vav; Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. | 0.694 |
Ncf1 | Cyba | ENSRNOP00000002028 | ENSRNOP00000017564 | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. | 0.999 |
Ncf1 | Cybb | ENSRNOP00000002028 | ENSRNOP00000031063 | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | Cytochrome b-245, beta polypeptide, isoform CRA_a. | 0.999 |
Ncf1 | Ncf4 | ENSRNOP00000002028 | ENSRNOP00000009544 | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | Similar to neutrophil cytosolic factor 4, isoform CRA_a. | 0.999 |
Ncf1 | Pak1 | ENSRNOP00000002028 | ENSRNOP00000073036 | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | Serine/threonine-protein kinase PAK 1; Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly phosphorylate BAD and protects cells against apoptosis. Activated by interaction with CDC42 and RAC1. Functions as GTPase effector that links the Rho-related GTPases CDC42 and RAC1 to the JNK MAP kinase pathway. Phosphorylates and activates MAP2K1, and thereby media [...] | 0.412 |
Ncf1 | Prex1 | ENSRNOP00000002028 | ENSRNOP00000009517 | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1. | 0.469 |
Ncf1 | Rac2 | ENSRNOP00000002028 | ENSRNOP00000009994 | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). | 0.999 |
Ncf1 | Tiam1 | ENSRNOP00000002028 | ENSRNOP00000044001 | Neutrophil cytosolic factor 1; NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). | TIAM Rac1-associated GEF 1. | 0.507 |