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Pex2 Pex2 Pex10 Pex10 Pex12 Pex12 Pex14 Pex14 Pex13 Pex13 LOC103690024 LOC103690024 LOC108348326 LOC108348326 Pex6 Pex6 Pex7 Pex7 LOC100911356 LOC100911356 Pex26 Pex26
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Pex2Peroxisome biogenesis factor 2; Somewhat implicated in the biogenesis of peroxisomes; Belongs to the pex2/pex10/pex12 family. (305 aa)    
Predicted Functional Partners:
Pex10
Peroxisomal biogenesis factor 10.
   
 0.985
Pex12
Peroxisome assembly protein 12; Required for protein import into peroxisomes.
   
 0.975
Pex14
Peroxisomal membrane protein PEX14; Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin.
   
 0.952
Pex13
Peroxisomal biogenesis factor 13 (Predicted).
   
 0.917
LOC103690024
Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
    
 0.889
LOC108348326
Peroxisome assembly protein 12.
   
 
 0.874
Pex6
Peroxisome assembly factor 2; Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor. Probably required for protein import into peroxisomes. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes (By similarity).
   
 
 0.860
Pex7
Peroxisomal biogenesis factor 7.
   
 
 0.848
LOC100911356
Peroxisomal biogenesis factor 19; Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
   
 0.840
Pex26
Similar to peroxisome biogenesis factor 26.
   
 
 0.836
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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