node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Alkbh3 | Dnajc24 | ENSRNOP00000030278 | ENSRNOP00000006431 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A). Repairs alkylated DNA containing 1- methyladenosine (m1A) and 3-methylcytosine (m3C) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated m3C within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3. Also acts on RNA. Demethylates N(1)-methyladenosine (m1A) RNA, an epigenetic internal modification of [...] | DnaJ heat shock protein family (Hsp40) member C24. | 0.419 |
Alkbh3 | Oaf | ENSRNOP00000030278 | ENSRNOP00000012825 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A). Repairs alkylated DNA containing 1- methyladenosine (m1A) and 3-methylcytosine (m3C) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated m3C within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3. Also acts on RNA. Demethylates N(1)-methyladenosine (m1A) RNA, an epigenetic internal modification of [...] | Out at first protein homolog; Belongs to the OAF family. | 0.473 |
Dnajc24 | Alkbh3 | ENSRNOP00000006431 | ENSRNOP00000030278 | DnaJ heat shock protein family (Hsp40) member C24. | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; Dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A). Repairs alkylated DNA containing 1- methyladenosine (m1A) and 3-methylcytosine (m3C) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated m3C within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3. Also acts on RNA. Demethylates N(1)-methyladenosine (m1A) RNA, an epigenetic internal modification of [...] | 0.419 |
Dnajc24 | Gemin2 | ENSRNOP00000006431 | ENSRNOP00000006137 | DnaJ heat shock protein family (Hsp40) member C24. | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | 0.552 |
Dnajc24 | Ildr2 | ENSRNOP00000006431 | ENSRNOP00000036628 | DnaJ heat shock protein family (Hsp40) member C24. | Immunoglobulin-like domain-containing receptor 2. | 0.588 |
Dnajc24 | Lemd2 | ENSRNOP00000006431 | ENSRNOP00000036495 | DnaJ heat shock protein family (Hsp40) member C24. | LEM domain nuclear envelope protein 2. | 0.704 |
Dnajc24 | Oaf | ENSRNOP00000006431 | ENSRNOP00000012825 | DnaJ heat shock protein family (Hsp40) member C24. | Out at first protein homolog; Belongs to the OAF family. | 0.609 |
Gemin2 | Dnajc24 | ENSRNOP00000006137 | ENSRNOP00000006431 | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | DnaJ heat shock protein family (Hsp40) member C24. | 0.552 |
Gemin2 | Ildr2 | ENSRNOP00000006137 | ENSRNOP00000036628 | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | Immunoglobulin-like domain-containing receptor 2. | 0.415 |
Gemin2 | Lemd2 | ENSRNOP00000006137 | ENSRNOP00000036495 | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | LEM domain nuclear envelope protein 2. | 0.590 |
Gemin2 | Oaf | ENSRNOP00000006137 | ENSRNOP00000012825 | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | Out at first protein homolog; Belongs to the OAF family. | 0.429 |
Ildr2 | Dnajc24 | ENSRNOP00000036628 | ENSRNOP00000006431 | Immunoglobulin-like domain-containing receptor 2. | DnaJ heat shock protein family (Hsp40) member C24. | 0.588 |
Ildr2 | Gemin2 | ENSRNOP00000036628 | ENSRNOP00000006137 | Immunoglobulin-like domain-containing receptor 2. | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | 0.415 |
Ildr2 | Lemd2 | ENSRNOP00000036628 | ENSRNOP00000036495 | Immunoglobulin-like domain-containing receptor 2. | LEM domain nuclear envelope protein 2. | 0.472 |
Ildr2 | Oaf | ENSRNOP00000036628 | ENSRNOP00000012825 | Immunoglobulin-like domain-containing receptor 2. | Out at first protein homolog; Belongs to the OAF family. | 0.499 |
Klhl14 | Oaf | ENSRNOP00000020697 | ENSRNOP00000012825 | Kelch-like family member 14. | Out at first protein homolog; Belongs to the OAF family. | 0.504 |
Lemd2 | Dnajc24 | ENSRNOP00000036495 | ENSRNOP00000006431 | LEM domain nuclear envelope protein 2. | DnaJ heat shock protein family (Hsp40) member C24. | 0.704 |
Lemd2 | Gemin2 | ENSRNOP00000036495 | ENSRNOP00000006137 | LEM domain nuclear envelope protein 2. | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | 0.590 |
Lemd2 | Ildr2 | ENSRNOP00000036495 | ENSRNOP00000036628 | LEM domain nuclear envelope protein 2. | Immunoglobulin-like domain-containing receptor 2. | 0.472 |
Lemd2 | Oaf | ENSRNOP00000036495 | ENSRNOP00000012825 | LEM domain nuclear envelope protein 2. | Out at first protein homolog; Belongs to the OAF family. | 0.565 |