Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Foxf1 | Pitx1 | ENSRNOP00000065868 | ENSRNOP00000015307 | Forkhead box F1. | Pituitary homeobox 1; Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. | 0.590 |
| Foxf1 | Pou1f1 | ENSRNOP00000065868 | ENSRNOP00000000905 | Forkhead box F1. | Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'. Belongs to the POU transcription factor family. Class-1 subfamily. | 0.553 |
| Foxf1 | Tbx4 | ENSRNOP00000065868 | ENSRNOP00000004736 | Forkhead box F1. | T-box transcription factor 4. | 0.494 |
| Fshb | Lhx3 | ENSRNOP00000006512 | ENSRNOP00000044069 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | RCG45383, isoform CRA_b. | 0.537 |
| Fshb | Lhx4 | ENSRNOP00000006512 | ENSRNOP00000060479 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | LIM homeobox 4. | 0.409 |
| Fshb | Nr5a1 | ENSRNOP00000006512 | ENSRNOP00000017651 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Steroidogenic factor 1; Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity. Binds phosphatidy [...] | 0.691 |
| Fshb | Pitx1 | ENSRNOP00000006512 | ENSRNOP00000015307 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Pituitary homeobox 1; Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. | 0.628 |
| Fshb | Pou1f1 | ENSRNOP00000006512 | ENSRNOP00000000905 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'. Belongs to the POU transcription factor family. Class-1 subfamily. | 0.691 |
| Fshb | Tbx19 | ENSRNOP00000006512 | ENSRNOP00000062131 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | T-box transcription factor 19. | 0.618 |
| Fshb | Tshb | ENSRNOP00000006512 | ENSRNOP00000022575 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Thyrotropin subunit beta; Indispensable for the control of thyroid structure and metabolism. | 0.454 |
| Lhx3 | Fshb | ENSRNOP00000044069 | ENSRNOP00000006512 | RCG45383, isoform CRA_b. | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | 0.537 |
| Lhx3 | Nr5a1 | ENSRNOP00000044069 | ENSRNOP00000017651 | RCG45383, isoform CRA_b. | Steroidogenic factor 1; Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity. Binds phosphatidy [...] | 0.428 |
| Lhx3 | Pitx1 | ENSRNOP00000044069 | ENSRNOP00000015307 | RCG45383, isoform CRA_b. | Pituitary homeobox 1; Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. | 0.727 |
| Lhx3 | Pou1f1 | ENSRNOP00000044069 | ENSRNOP00000000905 | RCG45383, isoform CRA_b. | Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'. Belongs to the POU transcription factor family. Class-1 subfamily. | 0.758 |
| Lhx3 | Six1 | ENSRNOP00000044069 | ENSRNOP00000037345 | RCG45383, isoform CRA_b. | Sine oculis homeobox homolog 1 (Drosophila). | 0.438 |
| Lhx3 | Tbx19 | ENSRNOP00000044069 | ENSRNOP00000062131 | RCG45383, isoform CRA_b. | T-box transcription factor 19. | 0.645 |
| Lhx3 | Tshb | ENSRNOP00000044069 | ENSRNOP00000022575 | RCG45383, isoform CRA_b. | Thyrotropin subunit beta; Indispensable for the control of thyroid structure and metabolism. | 0.563 |
| Lhx4 | Fshb | ENSRNOP00000060479 | ENSRNOP00000006512 | LIM homeobox 4. | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | 0.409 |
| Lhx4 | Pitx1 | ENSRNOP00000060479 | ENSRNOP00000015307 | LIM homeobox 4. | Pituitary homeobox 1; Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. | 0.696 |
| Lhx4 | Pou1f1 | ENSRNOP00000060479 | ENSRNOP00000000905 | LIM homeobox 4. | Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'. Belongs to the POU transcription factor family. Class-1 subfamily. | 0.736 |
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