STRINGSTRING
Mrgprf Mrgprf Cnn1 Cnn1 Efemp2 Efemp2 Copz2 Copz2 Vgll3 Vgll3 Zdhhc13 Zdhhc13 Fkbp10 Fkbp10 Prrx2 Prrx2 Atoh8 Atoh8 Tgfb1i1 Tgfb1i1 LOC108348293 LOC108348293
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
MrgprfMas-related G-protein coupled receptor member F; Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity). (343 aa)    
Predicted Functional Partners:
Cnn1
Calponin-1; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
   
    0.676
Efemp2
EGF-containing fibulin extracellular matrix protein 2.
   
  
 0.644
Copz2
Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
   
  
 0.629
Vgll3
Vestigial-like family member 3.
   
  
 0.613
Zdhhc13
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
 0.608
Fkbp10
Peptidylprolyl isomerase.
   
  
 0.603
Prrx2
Paired-related homeobox 2.
   
 
 0.598
Atoh8
Similar to bHLH factor Math6 (Predicted).
   
  
 0.586
Tgfb1i1
Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. [...]
   
  
 0.581
LOC108348293
Uncharacterized LOC108348293.
      
 0.581
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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