node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Far2 | Rassf4 | ENSRNOP00000002528 | ENSRNOP00000018101 | Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | 0.437 |
Islr2 | Rassf4 | ENSRNOP00000064244 | ENSRNOP00000018101 | Immunoglobulin superfamily-containing leucine-rich repeat 2. | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | 0.502 |
Jph4 | Rassf4 | ENSRNOP00000034702 | ENSRNOP00000018101 | Junctophilin-4; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory (By similarity). | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | 0.463 |
Jph4 | Tmem178a | ENSRNOP00000034702 | ENSRNOP00000010927 | Junctophilin-4; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory (By similarity). | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | 0.431 |
Olr1555 | RGD1561318 | ENSRNOP00000069964 | ENSRNOP00000069729 | Olfactory receptor. | Similar to SET domain-containing protein. | 0.787 |
Olr1555 | Rassf4 | ENSRNOP00000069964 | ENSRNOP00000018101 | Olfactory receptor. | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | 0.506 |
Pcdhb21 | Rassf4 | ENSRNOP00000046461 | ENSRNOP00000018101 | Protocadherin beta 21. | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | 0.509 |
RGD1561318 | Olr1555 | ENSRNOP00000069729 | ENSRNOP00000069964 | Similar to SET domain-containing protein. | Olfactory receptor. | 0.787 |
RGD1561318 | Rassf4 | ENSRNOP00000069729 | ENSRNOP00000018101 | Similar to SET domain-containing protein. | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | 0.508 |
Rassf2 | Rassf4 | ENSRNOP00000028883 | ENSRNOP00000018101 | Ras association domain-containing protein 2; Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation (By similarity). | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | 0.902 |
Rassf2 | Stk3 | ENSRNOP00000028883 | ENSRNOP00000062778 | Ras association domain-containing protein 2; Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation (By similarity). | Serine/threonine-protein kinase 3 20kDa subunit; Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regul [...] | 0.973 |
Rassf2 | Stk4 | ENSRNOP00000028883 | ENSRNOP00000061873 | Ras association domain-containing protein 2; Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation (By similarity). | Serine/threonine kinase 4 (Predicted). | 0.815 |
Rassf4 | Far2 | ENSRNOP00000018101 | ENSRNOP00000002528 | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. | 0.437 |
Rassf4 | Islr2 | ENSRNOP00000018101 | ENSRNOP00000064244 | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | Immunoglobulin superfamily-containing leucine-rich repeat 2. | 0.502 |
Rassf4 | Jph4 | ENSRNOP00000018101 | ENSRNOP00000034702 | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | Junctophilin-4; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory (By similarity). | 0.463 |
Rassf4 | Olr1555 | ENSRNOP00000018101 | ENSRNOP00000069964 | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | Olfactory receptor. | 0.506 |
Rassf4 | Pcdhb21 | ENSRNOP00000018101 | ENSRNOP00000046461 | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | Protocadherin beta 21. | 0.509 |
Rassf4 | RGD1561318 | ENSRNOP00000018101 | ENSRNOP00000069729 | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | Similar to SET domain-containing protein. | 0.508 |
Rassf4 | Rassf2 | ENSRNOP00000018101 | ENSRNOP00000028883 | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | Ras association domain-containing protein 2; Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation (By similarity). | 0.902 |
Rassf4 | Stk3 | ENSRNOP00000018101 | ENSRNOP00000062778 | Ras association domain-containing protein 4; Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest (By similarity). | Serine/threonine-protein kinase 3 20kDa subunit; Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regul [...] | 0.954 |