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Bpifa2 Bpifa2 Bpifb4 Bpifb4 Pip Pip Bpifa6 Bpifa6 Bpifa5 Bpifa5 Oprpn Oprpn Ca6 Ca6 Bpifb2 Bpifb2 Spt1 Spt1 Amelx Amelx Bpifb1 Bpifb1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bpifa2BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. Plunc family. (235 aa)    
Predicted Functional Partners:
Bpifb4
BPI fold-containing family B member 4; May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received (By similarity).
   
 
 0.771
Pip
Prolactin-inducible protein homolog; Belongs to the PIP family.
   
  
 0.750
Bpifa6
BPI fold-containing family A, member 6.
  
  
 0.745
Bpifa5
BPI fold-containing family A, member 5.
   
  
 0.721
Oprpn
Opiorphin prepropeptide.
   
  
 0.711
Ca6
Carbonic anhydrase 6; Belongs to the alpha-carbonic anhydrase family.
   
  
 0.710
Bpifb2
Bactericidal/permeability-increasing protein-like 1 (Predicted).
   
 
 0.684
Spt1
Salivary protein 1.
   
  
 0.680
Amelx
Amelogenin, X isoform; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.
   
    0.671
Bpifb1
BPI fold-containing family B member 1; May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS (By similarity); Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
     
 0.662
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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