Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cdh5 | Cldn5 | ENSRNOP00000017983 | ENSRNOP00000064048 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Claudin-5; Plays a major role in tight junction-specific obliteration of the intercellular space. | 0.961 |
| Cdh5 | Flt4 | ENSRNOP00000017983 | ENSRNOP00000003519 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by [...] | 0.905 |
| Cdh5 | Kdr | ENSRNOP00000017983 | ENSRNOP00000066886 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular grow [...] | 0.994 |
| Cdh5 | LOC100911068 | ENSRNOP00000017983 | ENSRNOP00000057050 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Roundabout homolog 4-like. | 0.614 |
| Cdh5 | Robo4 | ENSRNOP00000017983 | ENSRNOP00000044365 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Roundabout homolog 4; Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function (By similarity); Belongs to the immunoglobulin superfamily. ROBO family. | 0.614 |
| Cdh5 | Sox18 | ENSRNOP00000017983 | ENSRNOP00000021790 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | SRY (Sex determining region Y)-box 18. | 0.715 |
| Cdh5 | Vegfc | ENSRNOP00000017983 | ENSRNOP00000015529 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | Vascular endothelial growth factor C; Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates KDR/VEGFR2 and FLT4/VEGFR3 receptors. | 0.523 |
| Cldn5 | Cdh5 | ENSRNOP00000064048 | ENSRNOP00000017983 | Claudin-5; Plays a major role in tight junction-specific obliteration of the intercellular space. | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | 0.961 |
| Cldn5 | Kdr | ENSRNOP00000064048 | ENSRNOP00000066886 | Claudin-5; Plays a major role in tight junction-specific obliteration of the intercellular space. | Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular grow [...] | 0.644 |
| Cldn5 | LOC100911068 | ENSRNOP00000064048 | ENSRNOP00000057050 | Claudin-5; Plays a major role in tight junction-specific obliteration of the intercellular space. | Roundabout homolog 4-like. | 0.768 |
| Cldn5 | Rasip1 | ENSRNOP00000064048 | ENSRNOP00000034336 | Claudin-5; Plays a major role in tight junction-specific obliteration of the intercellular space. | Ras interacting protein 1 (Predicted), isoform CRA_a. | 0.418 |
| Cldn5 | Robo4 | ENSRNOP00000064048 | ENSRNOP00000044365 | Claudin-5; Plays a major role in tight junction-specific obliteration of the intercellular space. | Roundabout homolog 4; Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function (By similarity); Belongs to the immunoglobulin superfamily. ROBO family. | 0.772 |
| Cldn5 | Sox18 | ENSRNOP00000064048 | ENSRNOP00000021790 | Claudin-5; Plays a major role in tight junction-specific obliteration of the intercellular space. | SRY (Sex determining region Y)-box 18. | 0.977 |
| Cyyr1 | Kdr | ENSRNOP00000002109 | ENSRNOP00000066886 | Cysteine and tyrosine-rich protein 1. | Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular grow [...] | 0.734 |
| Cyyr1 | Rasip1 | ENSRNOP00000002109 | ENSRNOP00000034336 | Cysteine and tyrosine-rich protein 1. | Ras interacting protein 1 (Predicted), isoform CRA_a. | 0.575 |
| Cyyr1 | Sox18 | ENSRNOP00000002109 | ENSRNOP00000021790 | Cysteine and tyrosine-rich protein 1. | SRY (Sex determining region Y)-box 18. | 0.718 |
| Flt4 | Cdh5 | ENSRNOP00000003519 | ENSRNOP00000017983 | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by [...] | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. | 0.905 |
| Flt4 | Kdr | ENSRNOP00000003519 | ENSRNOP00000066886 | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by [...] | Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular grow [...] | 0.975 |
| Flt4 | Nr2f2 | ENSRNOP00000003519 | ENSRNOP00000014152 | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by [...] | COUP transcription factor 2; Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A (By similarity). | 0.536 |
| Flt4 | Sox18 | ENSRNOP00000003519 | ENSRNOP00000021790 | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by [...] | SRY (Sex determining region Y)-box 18. | 0.709 |
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