STRINGSTRING
Isoc1 Isoc1 Olr297 Olr297 Samd12 Samd12 Hsdl2 Hsdl2 Naprt Naprt Serinc5 Serinc5 Dhrs2 Dhrs2 Mroh6 Mroh6 Phldb3 Phldb3 Zadh2 Zadh2 St8sia5 St8sia5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Isoc1Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. (297 aa)    
Predicted Functional Partners:
Olr297
Olfactory receptor 297.
      
 0.664
Samd12
Sterile alpha motif domain-containing 12.
      
 0.646
Hsdl2
Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 0.630
Naprt
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis.
  
 
 0.612
Serinc5
Serine incorporator 5; Restriction factor required to restrict infectivity of gammaretroviruses: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm (By similarity). Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes; Belongs to the TDE1 family.
   
  
 0.568
Dhrs2
Dehydrogenase/reductase 2.
   
 0.565
Mroh6
Maestro heat-like repeat family member 6.
  
 
 0.565
Phldb3
Pleckstrin homology-like domain, family B, member 3.
      
 0.560
Zadh2
Zinc-binding alcohol dehydrogenase, domain-containing 2.
   
  
 0.554
St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5; Belongs to the glycosyltransferase 29 family.
      
 0.528
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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