STRINGSTRING
Sec1 Sec1 B3gnt3 B3gnt3 Gcnt2 Gcnt2 Fut9 Fut9 St3gal2 St3gal2 St3gal4 St3gal4 Fut4 Fut4 B3galt5 B3galt5 B3galt2 B3galt2 B3galt1 B3galt1 B3gnt2 B3gnt2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
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[Homology]
Score
Sec1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (299 aa)    
Predicted Functional Partners:
B3gnt3
Hexosyltransferase.
   
 
 0.926
Gcnt2
I-branching beta-1,6-acetylglucosaminyltransferase family polypeptide 3.
     
 0.924
Fut9
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9; Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal lactosamine unit of a glycoprotein or a glycolipid-linked polylactosamine chains through an alpha-1,3 glycosidic linkage and participates in particular to the Lewis x (Lex)/CD15 epitope biosynthesis in neurons which allows cell differentiation, cell adhesion, and initiation of neurite outgrowth. Also fucosylates di-, tri- and tetraantennary N- glycans linked to glycoproteins and the inner lact [...]
   
 
 0.915
St3gal2
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2; Responsible for the synthesis of the sequence NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values.
     
 0.913
St3gal4
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4; Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4- GlcNAc-, and NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant.
     
 0.912
Fut4
Alpha-(1,3)-fucosyltransferase 4; May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
   
 
 0.911
B3galt5
Hexosyltransferase.
   
 
 0.910
B3galt2
Hexosyltransferase.
   
 
 0.909
B3galt1
Hexosyltransferase.
   
 
 0.909
B3gnt2
Hexosyltransferase.
   
 
 0.909
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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