STRINGSTRING
Zar1 Zar1 Nlrp5 Nlrp5 H1f8 H1f8 Npm2 Npm2 Ankmy1 Ankmy1 Gdf9 Gdf9 Ooep Ooep Padi6 Padi6 Bmp15 Bmp15 Zp3 Zp3 Zfp518a Zfp518a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Zar1Zygote arrest protein 1; Essential for female fertility. May play a role in the oocyte-to-embryo transition (By similarity); Belongs to the ZAR1 family. (361 aa)    
Predicted Functional Partners:
Nlrp5
NACHT, leucine rich repeat and PYD containing 5 (Predicted).
      
 0.736
H1f8
Similar to oocyte-specific linker histone H1oo (Predicted).
   
  
 0.704
Npm2
Nucleophosmin/nucleoplasmin 2.
      
 0.702
Ankmy1
Ankyrin repeat and MYND domain-containing 1.
      
 0.693
Gdf9
Growth differentiation factor 9.
      
 0.672
Ooep
Oocyte-expressed protein.
      
 0.627
Padi6
Peptidyl arginine deiminase 6.
      
 0.582
Bmp15
Bone morphogenetic protein 15.
      
 0.575
Zp3
Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
   
  
 0.539
Zfp518a
Zinc finger protein 518A; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
      
 0.526
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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