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Prss30 Prss30 Tas2r134 Tas2r134 Trmt9b Trmt9b Zgrf1 Zgrf1 Zgrf1-2 Zgrf1-2 Lonrf1 Lonrf1 Eme2 Eme2 Purg Purg Trmt13 Trmt13 Tti2 Tti2 Trmt11 Trmt11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Prss30Serine protease 30; Selectively cleaves synthetic peptide substrates of trypsin. Activates the epithelial sodium channel ENaC. Belongs to the peptidase S1 family. (304 aa)    
Predicted Functional Partners:
Tas2r134
Taste receptor type 2 member 134; Putative taste receptor which may play a role in the perception of bitterness; Belongs to the G-protein coupled receptor T2R family.
      
 0.576
Trmt9b
Similar to 6430573F11Rik protein (Predicted), isoform CRA_d.
    
 
 0.561
Zgrf1
Zinc finger, GRF-type-containing 1.
    
 
 0.527
Zgrf1-2
AAA_12 domain-containing protein.
    
 
 0.527
Lonrf1
LON peptidase N-terminal domain and ring finger 1.
      
 0.521
Eme2
Essential meiotic structure-specific endonuclease subunit 2.
   
 
 0.509
Purg
Purine-rich element-binding protein G.
      
 0.499
Trmt13
tRNA methyltransferase 13 homolog.
      
 0.497
Tti2
TELO2-interacting protein 2; Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs (By similarity); Belongs to the TTI2 family.
    
 
 0.451
Trmt11
tRNA (guanine(10)-N2)-methyltransferase homolog; Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
   
 
 0.446
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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