node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dguok | Immt | ENSRNOP00000062535 | ENSRNOP00000069486 | Deoxyguanosine kinase (Predicted), isoform CRA_a. | MICOS complex subunit Mic60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. | 0.428 |
Dguok | Mpv17 | ENSRNOP00000062535 | ENSRNOP00000037647 | Deoxyguanosine kinase (Predicted), isoform CRA_a. | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | 0.765 |
Dguok | Polg | ENSRNOP00000062535 | ENSRNOP00000047900 | Deoxyguanosine kinase (Predicted), isoform CRA_a. | DNA polymerase subunit gamma-1; Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA (By similarity). | 0.766 |
Dguok | Rrm2b | ENSRNOP00000062535 | ENSRNOP00000038047 | Deoxyguanosine kinase (Predicted), isoform CRA_a. | Ribonucleotide reductase regulatory TP53-inducible subunit M2B. | 0.823 |
Dguok | Sucla2 | ENSRNOP00000062535 | ENSRNOP00000060229 | Deoxyguanosine kinase (Predicted), isoform CRA_a. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.750 |
Dguok | Suclg1 | ENSRNOP00000062535 | ENSRNOP00000007624 | Deoxyguanosine kinase (Predicted), isoform CRA_a. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.794 |
Immt | Dguok | ENSRNOP00000069486 | ENSRNOP00000062535 | MICOS complex subunit Mic60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. | Deoxyguanosine kinase (Predicted), isoform CRA_a. | 0.428 |
Immt | Mpv17 | ENSRNOP00000069486 | ENSRNOP00000037647 | MICOS complex subunit Mic60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | 0.623 |
Immt | Suclg1 | ENSRNOP00000069486 | ENSRNOP00000007624 | MICOS complex subunit Mic60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.478 |
Mpv17 | Dguok | ENSRNOP00000037647 | ENSRNOP00000062535 | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | Deoxyguanosine kinase (Predicted), isoform CRA_a. | 0.765 |
Mpv17 | Immt | ENSRNOP00000037647 | ENSRNOP00000069486 | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | MICOS complex subunit Mic60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. | 0.623 |
Mpv17 | Mpv17l | ENSRNOP00000037647 | ENSRNOP00000004384 | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | Mpv17 transgene, kidney disease mutant-like (Predicted), isoform CRA_b; Belongs to the peroxisomal membrane protein PXMP2/4 family. | 0.909 |
Mpv17 | Mpv17l2 | ENSRNOP00000037647 | ENSRNOP00000026271 | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | MPV17 mitochondrial inner membrane protein-like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. | 0.911 |
Mpv17 | Polg | ENSRNOP00000037647 | ENSRNOP00000047900 | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | DNA polymerase subunit gamma-1; Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA (By similarity). | 0.623 |
Mpv17 | Rrm2b | ENSRNOP00000037647 | ENSRNOP00000038047 | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | Ribonucleotide reductase regulatory TP53-inducible subunit M2B. | 0.635 |
Mpv17 | Sucla2 | ENSRNOP00000037647 | ENSRNOP00000060229 | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.626 |
Mpv17 | Suclg1 | ENSRNOP00000037647 | ENSRNOP00000007624 | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.658 |
Mpv17 | Tk2 | ENSRNOP00000037647 | ENSRNOP00000017269 | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | Thymidine kinase 2, mitochondrial (Predicted). | 0.556 |
Mpv17 | Zfp78 | ENSRNOP00000037647 | ENSRNOP00000037545 | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | Zinc finger protein 78. | 0.571 |
Mpv17l | Mpv17 | ENSRNOP00000004384 | ENSRNOP00000037647 | Mpv17 transgene, kidney disease mutant-like (Predicted), isoform CRA_b; Belongs to the peroxisomal membrane protein PXMP2/4 family. | Protein Mpv17; Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance (By similarity). May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (By similarity); Belongs to the peroxisomal membrane protein PXMP2/4 family. | 0.909 |