node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Eefsec | Eif4a3 | ENSRNOP00000017323 | ENSRNOP00000066302 | Similar to MJ0495-like protein SelB (Predicted), isoform CRA_a. | Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] | 0.666 |
Eefsec | Pstk | ENSRNOP00000017323 | ENSRNOP00000027967 | Similar to MJ0495-like protein SelB (Predicted), isoform CRA_a. | Phosphoseryl-tRNA kinase. | 0.919 |
Eefsec | Rpl30 | ENSRNOP00000017323 | ENSRNOP00000054398 | Similar to MJ0495-like protein SelB (Predicted), isoform CRA_a. | 60S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family. | 0.884 |
Eefsec | Secisbp2 | ENSRNOP00000017323 | ENSRNOP00000039532 | Similar to MJ0495-like protein SelB (Predicted), isoform CRA_a. | Selenocysteine insertion sequence-binding protein 2; Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB. | 0.982 |
Eefsec | Selenok | ENSRNOP00000017323 | ENSRNOP00000020284 | Similar to MJ0495-like protein SelB (Predicted), isoform CRA_a. | Selenoprotein K; Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (By similarity). Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins (By similarity). Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation (By similarity). Together with ZDHHC6, required for palmitoylation of ITPR1 in immune cells, leading to regulate ITPR1 stability and function. Plays a role in protection o [...] | 0.640 |
Eefsec | Selenon | ENSRNOP00000017323 | ENSRNOP00000022921 | Similar to MJ0495-like protein SelB (Predicted), isoform CRA_a. | Selenoprotein N. | 0.699 |
Eefsec | Selenot | ENSRNOP00000017323 | ENSRNOP00000072567 | Similar to MJ0495-like protein SelB (Predicted), isoform CRA_a. | Thioredoxin reductase-like selenoprotein T; Selenoprotein with thioredoxin reductase-like oxidoreductase activity. Protects dopaminergic neurons against oxidative stress ans cell death (By similarity). Involved in ADCYAP1/PACAP-induced calcium mobilization and neuroendocrine secretion. Plays a role in fibroblast anchorage and redox regulation (By similarity). In gastric smooth muscle, modulates the contraction processes through the regulation of calcium release and MYLK activation. In pancreatic islets, involved in the control of glucose homeostasis, contributes to prolonged ADCYAP1/PA [...] | 0.799 |
Eefsec | Sepsecs | ENSRNOP00000017323 | ENSRNOP00000065651 | Similar to MJ0495-like protein SelB (Predicted), isoform CRA_a. | O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. | 0.869 |
Eefsec | Trnau1ap | ENSRNOP00000017323 | ENSRNOP00000070906 | Similar to MJ0495-like protein SelB (Predicted), isoform CRA_a. | tRNA selenocysteine 1-associated protein 1; Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity); Belongs to the RRM TRSPAP family. | 0.913 |
Eefsec | Txnrd1 | ENSRNOP00000017323 | ENSRNOP00000013612 | Similar to MJ0495-like protein SelB (Predicted), isoform CRA_a. | Thioredoxin reductase 1, cytoplasmic. | 0.487 |
Eif4a3 | Eefsec | ENSRNOP00000066302 | ENSRNOP00000017323 | Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] | Similar to MJ0495-like protein SelB (Predicted), isoform CRA_a. | 0.666 |
Eif4a3 | Pstk | ENSRNOP00000066302 | ENSRNOP00000027967 | Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] | Phosphoseryl-tRNA kinase. | 0.522 |
Eif4a3 | Rpl30 | ENSRNOP00000066302 | ENSRNOP00000054398 | Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] | 60S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family. | 0.573 |
Eif4a3 | Secisbp2 | ENSRNOP00000066302 | ENSRNOP00000039532 | Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] | Selenocysteine insertion sequence-binding protein 2; Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB. | 0.835 |
Eif4a3 | Selenok | ENSRNOP00000066302 | ENSRNOP00000020284 | Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] | Selenoprotein K; Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (By similarity). Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins (By similarity). Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation (By similarity). Together with ZDHHC6, required for palmitoylation of ITPR1 in immune cells, leading to regulate ITPR1 stability and function. Plays a role in protection o [...] | 0.447 |
Eif4a3 | Selenon | ENSRNOP00000066302 | ENSRNOP00000022921 | Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] | Selenoprotein N. | 0.403 |
Eif4a3 | Sepsecs | ENSRNOP00000066302 | ENSRNOP00000065651 | Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] | O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. | 0.536 |
Eif4a3 | Trnau1ap | ENSRNOP00000066302 | ENSRNOP00000070906 | Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] | tRNA selenocysteine 1-associated protein 1; Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity); Belongs to the RRM TRSPAP family. | 0.615 |
Pstk | Eefsec | ENSRNOP00000027967 | ENSRNOP00000017323 | Phosphoseryl-tRNA kinase. | Similar to MJ0495-like protein SelB (Predicted), isoform CRA_a. | 0.919 |
Pstk | Eif4a3 | ENSRNOP00000027967 | ENSRNOP00000066302 | Phosphoseryl-tRNA kinase. | Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] | 0.522 |