node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dhrs11 | Pigw | ENSRNOP00000038582 | ENSRNOP00000060195 | Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane (By similarity). Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins. | 0.807 |
Dhrs11 | Znhit3 | ENSRNOP00000038582 | ENSRNOP00000033107 | Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Similar to thyroid hormone receptor interactor 3, isoform CRA_d. | 0.778 |
Gpld1 | Pigl | ENSRNOP00000024196 | ENSRNOP00000004113 | Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane. | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol. Belongs to the PIGL family. | 0.908 |
Gpld1 | Pigw | ENSRNOP00000024196 | ENSRNOP00000060195 | Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane. | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane (By similarity). Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins. | 0.917 |
Pigc | Pigl | ENSRNOP00000035922 | ENSRNOP00000004113 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol. Belongs to the PIGL family. | 0.987 |
Pigc | Pigm | ENSRNOP00000035922 | ENSRNOP00000010551 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity). | 0.702 |
Pigc | Pign | ENSRNOP00000035922 | ENSRNOP00000020752 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | Phosphatidylinositol glycan anchor biosynthesis, class N. | 0.837 |
Pigc | Pigo | ENSRNOP00000035922 | ENSRNOP00000013213 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | Phosphatidylinositol glycan anchor biosynthesis, class O. | 0.840 |
Pigc | Pigv | ENSRNOP00000035922 | ENSRNOP00000000133 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | GPI mannosyltransferase 2; Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity); Belongs to the PIGV family. | 0.880 |
Pigc | Pigw | ENSRNOP00000035922 | ENSRNOP00000060195 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane (By similarity). Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins. | 0.871 |
Pigc | Pigx | ENSRNOP00000035922 | ENSRNOP00000042305 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | Phosphatidylinositol-glycan biosynthesis class X protein; Essential component of glycosylphosphatidylinositol- mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM. | 0.663 |
Pigl | Gpld1 | ENSRNOP00000004113 | ENSRNOP00000024196 | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol. Belongs to the PIGL family. | Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane. | 0.908 |
Pigl | Pigc | ENSRNOP00000004113 | ENSRNOP00000035922 | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol. Belongs to the PIGL family. | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | 0.987 |
Pigl | Pigm | ENSRNOP00000004113 | ENSRNOP00000010551 | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol. Belongs to the PIGL family. | GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity). | 0.861 |
Pigl | Pign | ENSRNOP00000004113 | ENSRNOP00000020752 | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol. Belongs to the PIGL family. | Phosphatidylinositol glycan anchor biosynthesis, class N. | 0.874 |
Pigl | Pigo | ENSRNOP00000004113 | ENSRNOP00000013213 | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol. Belongs to the PIGL family. | Phosphatidylinositol glycan anchor biosynthesis, class O. | 0.876 |
Pigl | Pigv | ENSRNOP00000004113 | ENSRNOP00000000133 | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol. Belongs to the PIGL family. | GPI mannosyltransferase 2; Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity); Belongs to the PIGV family. | 0.852 |
Pigl | Pigw | ENSRNOP00000004113 | ENSRNOP00000060195 | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol. Belongs to the PIGL family. | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane (By similarity). Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins. | 0.988 |
Pigl | Pigx | ENSRNOP00000004113 | ENSRNOP00000042305 | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol. Belongs to the PIGL family. | Phosphatidylinositol-glycan biosynthesis class X protein; Essential component of glycosylphosphatidylinositol- mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM. | 0.652 |
Pigm | Pigc | ENSRNOP00000010551 | ENSRNOP00000035922 | GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity). | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | 0.702 |