node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ncbp1 | Prpf38a | ENSRNOP00000038713 | ENSRNOP00000012635 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC [...] | PRP38 pre-mRNA processing factor 38 (Yeast) domain containing A (Predicted), isoform CRA_b. | 0.766 |
Ncbp1 | Prpf8 | ENSRNOP00000038713 | ENSRNOP00000073574 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC [...] | Pre-mRNA processing factor 8, isoform CRA_a. | 0.858 |
Ncbp1 | Rbm22 | ENSRNOP00000038713 | ENSRNOP00000026087 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC [...] | Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses; Belongs to the SLT11 family. | 0.528 |
Ncbp1 | Sf3a2 | ENSRNOP00000038713 | ENSRNOP00000026202 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC [...] | Splicing factor 3A subunit 2; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex. Interacts directly with the duplex formed by U2 snRNA and the intron. | 0.789 |
Ncbp1 | Sf3b2 | ENSRNOP00000038713 | ENSRNOP00000060335 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC [...] | Splicing factor 3b, subunit 2. | 0.806 |
Ncbp1 | Snw1 | ENSRNOP00000038713 | ENSRNOP00000054619 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC [...] | Similar to Nuclear protein SkiP (Ski-interacting protein) (Predicted). | 0.826 |
Ncbp1 | Srrm1 | ENSRNOP00000038713 | ENSRNOP00000073024 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC [...] | Serine and arginine repetitive matrix 1. | 0.828 |
Ncbp1 | Wbp11-2 | ENSRNOP00000038713 | ENSRNOP00000065287 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC [...] | WW domain-binding protein 11-like 1. | 0.763 |
Ppp1cb | Wbp11-2 | ENSRNOP00000006190 | ENSRNOP00000065287 | Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] | WW domain-binding protein 11-like 1. | 0.646 |
Pqbp1 | Wbp11-2 | ENSRNOP00000010536 | ENSRNOP00000065287 | Polyglutamine-binding protein 1; Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development. Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species. May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-in [...] | WW domain-binding protein 11-like 1. | 0.758 |
Prpf38a | Ncbp1 | ENSRNOP00000012635 | ENSRNOP00000038713 | PRP38 pre-mRNA processing factor 38 (Yeast) domain containing A (Predicted), isoform CRA_b. | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC [...] | 0.766 |
Prpf38a | Prpf8 | ENSRNOP00000012635 | ENSRNOP00000073574 | PRP38 pre-mRNA processing factor 38 (Yeast) domain containing A (Predicted), isoform CRA_b. | Pre-mRNA processing factor 8, isoform CRA_a. | 0.970 |
Prpf38a | Rbm22 | ENSRNOP00000012635 | ENSRNOP00000026087 | PRP38 pre-mRNA processing factor 38 (Yeast) domain containing A (Predicted), isoform CRA_b. | Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses; Belongs to the SLT11 family. | 0.642 |
Prpf38a | Sf3a2 | ENSRNOP00000012635 | ENSRNOP00000026202 | PRP38 pre-mRNA processing factor 38 (Yeast) domain containing A (Predicted), isoform CRA_b. | Splicing factor 3A subunit 2; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex. Interacts directly with the duplex formed by U2 snRNA and the intron. | 0.926 |
Prpf38a | Sf3b2 | ENSRNOP00000012635 | ENSRNOP00000060335 | PRP38 pre-mRNA processing factor 38 (Yeast) domain containing A (Predicted), isoform CRA_b. | Splicing factor 3b, subunit 2. | 0.926 |
Prpf38a | Snw1 | ENSRNOP00000012635 | ENSRNOP00000054619 | PRP38 pre-mRNA processing factor 38 (Yeast) domain containing A (Predicted), isoform CRA_b. | Similar to Nuclear protein SkiP (Ski-interacting protein) (Predicted). | 0.726 |
Prpf38a | Srrm1 | ENSRNOP00000012635 | ENSRNOP00000073024 | PRP38 pre-mRNA processing factor 38 (Yeast) domain containing A (Predicted), isoform CRA_b. | Serine and arginine repetitive matrix 1. | 0.722 |
Prpf38a | Wbp11-2 | ENSRNOP00000012635 | ENSRNOP00000065287 | PRP38 pre-mRNA processing factor 38 (Yeast) domain containing A (Predicted), isoform CRA_b. | WW domain-binding protein 11-like 1. | 0.706 |
Prpf8 | Ncbp1 | ENSRNOP00000073574 | ENSRNOP00000038713 | Pre-mRNA processing factor 8, isoform CRA_a. | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC [...] | 0.858 |
Prpf8 | Prpf38a | ENSRNOP00000073574 | ENSRNOP00000012635 | Pre-mRNA processing factor 8, isoform CRA_a. | PRP38 pre-mRNA processing factor 38 (Yeast) domain containing A (Predicted), isoform CRA_b. | 0.970 |