STRING 9.05 
  Pik3r2 protein (Rattus norvegicus) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
Pik3r2
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85 subunit beta)(PtdIns-3-kinase p85-beta); Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane (722 aa)
(Rattus norvegicus)
Predicted Functional Partners:
Irs2
insulin receptor substrate 2 (1327 aa)
     0.974
Irs1
Insulin receptor substrate 1 (IRS-1)(pp185); May mediate the control of various cellular proces [...] (1235 aa)
     0.970
Kit
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (978 aa)
      0.957
Pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153)(PI [...] (1070 aa)
     0.950
Gab2
GRB2-associated-binding protein 2 (Growth factor receptor bound protein 2-associated protein 2) [...] (639 aa)
     0.934
Akt1
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)(RAC-PK-alpha)(Protein kinase B)(PKB); G [...] (480 aa)
     0.924
Erbb3
Receptor tyrosine-protein kinase erbB-3 Precursor (c-erbB3)(EC 2.7.10.1); Binds and is activate [...] (1339 aa)
      0.923
Pi4kb
Phosphatidylinositol 4-kinase beta (PtdIns 4-kinase beta)(PI4K-beta)(PI4Kbeta)(EC 2.7.1.67); Ph [...] (816 aa)
       0.921
Pi4ka
phosphatidylinositol 4-kinase a (2046 aa)
       0.921
Irs3
insulin receptor substrate 3 (494 aa)
     0.920
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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