STRINGSTRING
ACPL_7075 ACPL_7075 ACPL_520 ACPL_520 ligD ligD ligC-2 ligC-2 ku ku ligC ligC ligB ligB ACPL_8276 ACPL_8276
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_7075DNA ligase (ATP); Predicted eukaryotic-type DNA primase. (341 aa)    
Predicted Functional Partners:
ACPL_520
ATP-dependent DNA ligase.
   
 0.978
ligD
ATP-dependent DNA ligase.
   
 0.977
ligC-2
ATP-dependent DNA ligase.
   
 0.932
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.897
ligC
ATP-dependent DNA ligase.
   
 0.792
ligB
ATP-dependent DNA ligase.
   
 0.790
ACPL_8276
Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.
 
   
 0.464
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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