STRINGSTRING
rnhA rnhA dnaQ dnaQ rnhB rnhB topA topA cafA cafA holA holA priC priC polA polA ruvC ruvC yaaJ yaaJ proC proC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
rnhARNase HI, degrades RNA of DNA-RNA hybrids, participates in DNA replication; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (155 aa)    
Predicted Functional Partners:
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
 
  
 0.957
rnhB
RNAse HII, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
 
 0.917
topA
DNA topoisomerase type I, omega protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, th [...]
   
 
 0.737
cafA
Bundles of cytoplasmic filaments; Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity).
      
 0.731
holA
DNA polymerase III, delta subunit; Residues 1 to 343 of 343 are 99.41 pct identical to residues 1 to 343 of 343 from Escherichia coli K-12 Strain MG1655: B0640.
      
 0.714
priC
Primosomal replication protein N'; Residues 1 to 175 of 175 are 97.71 pct identical to residues 1 to 175 of 175 from Escherichia coli K-12 Strain MG1655: B0467.
      
 0.700
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.700
ruvC
Holliday junction nuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity).
 
   
 0.695
yaaJ
Inner membrane transport protein; Residues 1 to 476 of 476 are 99.15 pct identical to residues 1 to 476 of 476 from Escherichia coli K-12 Strain MG1655: B0007.
      
 0.692
proC
Pyrroline-5-carboxylate reductase; Residues 1 to 269 of 269 are 99.62 pct identical to residues 1 to 269 of 269 from Escherichia coli K-12 Strain MG1655: B0386.
      0.663
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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