STRINGSTRING
aspC aspC mdh mdh icdA icdA pheA pheA tyrA tyrA gdhA gdhA gltB gltB putA putA hisC hisC purA purA argA argA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aspCAspartate aminotransferase; Residues 1 to 396 of 396 are 99.49 pct identical to residues 1 to 396 of 396 from Escherichia coli K-12 Strain MG1655: B0928. (396 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
   
 0.976
icdA
Isocitrate dehydrogenase, specific for NADP+; Residues 1 to 416 of 416 are 99.27 pct identical to residues 1 to 416 of 416 from Escherichia coli K-12 Strain MG1655: B1136.
   
 0.956
pheA
Chorismate mutase-P and prephenate dehydratase; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
    
 0.947
tyrA
Chorismate mutase-T and prephenate dehydrogenase; Residues 1 to 373 of 373 are 99.46 pct identical to residues 1 to 373 of 373 from Escherichia coli K-12 Strain MG1655: B2600.
    
 0.946
gdhA
NADP-specific glutamate dehydrogenase; Residues 1 to 447 of 447 are 99.32 pct identical to residues 1 to 447 of 447 from Escherichia coli K-12 Strain MG1655: B1761; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.934
gltB
Glutamate synthase, large subunit; Residues 1 to 1517 of 1517 are 99.53 pct identical to residues 1 to 1517 of 1517 from Escherichia coli K-12 Strain MG1655: B3212.
    
 0.917
putA
Proline dehydrogenase, P5C dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
 
 0.916
hisC
Histidinol-phosphate aminotransferase; Residues 1 to 356 of 356 are 99.43 pct identical to residues 1 to 356 of 356 from Escherichia coli K-12 Strain MG1655: B2021; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
   
 
 0.916
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.915
argA
N-acetylglutamate synthase; Residues 1 to 443 of 443 are 100.00 pct identical to residues 1 to 443 of 443 from Escherichia coli K-12 Strain MG1655: B2818; Belongs to the acetyltransferase family. ArgA subfamily.
     
 0.914
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.