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hsdM hsdM hsdS hsdS hsdR hsdR serB serB malQ malQ yjiS yjiS yjiA yjiA uvrB uvrB ybjD ybjD Z5899 Z5899 Orf-31 Orf-31
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hsdMPutative restriction modification enzyme M subunit (methylase); Residues 5 to 493 of 493 are 98.97 pct identical to residues 1 to 489 of 489 from GenPept 118 : gi|146396|gb|AAA23984.1| (L02505) restriction-modification enzyme type I M subunit [Escherichia coli]. (493 aa)    
Predicted Functional Partners:
hsdS
Putative restriction modification enzyme S subunit; Residues 1 to 584 of 584 are 53.75 pct identical to residues 1 to 578 of 578 from GenPept 118 : gi|40467|emb|CAA35604.1| (X17591) HsdS polypeptide, part of CfrA family [Citrobacter freundii].
 
 
 0.998
hsdR
Putative restriction modification enzyme R subunit (endonuclease); Residues 1 to 810 of 810 are 99.75 pct identical to residues 1 to 810 of 810 from GenPept 118 : gi|304894|gb|AAA23983.1| (L18758) EcoA type I restriction-modification enzyme R subunit [Escherichia coli].
 
   
 0.973
serB
Phosphoserine phosphatase; Catalyzes the dephosphorylation of phosphoserine (P-Ser).
  
  
 0.713
malQ
4-alpha-glucanotransferase (amylomaltase); Residues 1 to 694 of 694 are 98.84 pct identical to residues 1 to 694 of 694 from Escherichia coli K-12 Strain MG1655: B3416.
      
 0.701
yjiS
Orf, hypothetical protein; Residues 1 to 54 of 54 are 90.74 pct identical to residues 1 to 54 of 54 from Escherichia coli K-12 Strain MG1655: B4341.
      
 0.700
yjiA
Hypothetical protein; Residues 1 to 284 of 284 are 99.29 pct identical to residues 1 to 284 of 284 from Escherichia coli K-12 Strain MG1655: B4352.
      
 0.700
uvrB
DNA repair; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA [...]
    
 
 0.698
ybjD
Orf, hypothetical protein; Residues 1 to 552 of 552 are 99.63 pct identical to residues 1 to 552 of 552 from Escherichia coli K-12 Strain MG1655: B0876.
  
  
 0.627
Z5899
Putative ATP-dependent helicase; Residues 39 to 635 of 952 are 26.61 pct identical to residues 22 to 665 of 979 from GenPept 118 : gi|2822377|gb|AAC82883.1| (AF016485) ORF H1186 [Halobacterium sp. NRC-1].
 
   
 0.475
Orf-31
Orf; Residues 1 to 86 of 94 are 37.36 pct identical to residues 4 to 94 of 271 from GenPept 118 : gi|2314571|gb|AAD08442.1| (AE000639) H. pylori predicted coding region HP1397 [Helicobacter pylori 26695].
 
     0.459
Your Current Organism:
Escherichia coli O157H7 EDL933
NCBI taxonomy Id: 155864
Other names: E. coli O157:H7 str. EDL933, Escherichia coli O157:H7 EDL933, Escherichia coli O157:H7 str. EDL933, Escherichia coli O157:H7 strain EDL933
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