node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bacA | murG | spr0413 | spr0604 | A lipid kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.695 |
bacA | spr0434 | spr0413 | spr0434 | A lipid kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | Conserved hypothetical protein; Probable phosphatidic acid phosphatase. | 0.919 |
bacA | uppS | spr0413 | spr0240 | A lipid kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.963 |
cdsA | eep | spr0241 | spr0242 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Determinant for enhanced expression of pheromone; Belongs to the peptidase M50B family. | 0.863 |
cdsA | murG | spr0241 | spr0604 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.564 |
cdsA | proS | spr0241 | spr0243 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.766 |
cdsA | ruvB | spr0241 | spr0238 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Branch migration of Holliday structures; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.438 |
cdsA | uppS | spr0241 | spr0240 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.958 |
eep | cdsA | spr0242 | spr0241 | Determinant for enhanced expression of pheromone; Belongs to the peptidase M50B family. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.863 |
eep | frr | spr0242 | spr0846 | Determinant for enhanced expression of pheromone; Belongs to the peptidase M50B family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.508 |
eep | ispA | spr0242 | spr1087 | Determinant for enhanced expression of pheromone; Belongs to the peptidase M50B family. | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.529 |
eep | proS | spr0242 | spr0243 | Determinant for enhanced expression of pheromone; Belongs to the peptidase M50B family. | Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.862 |
eep | ruvB | spr0242 | spr0238 | Determinant for enhanced expression of pheromone; Belongs to the peptidase M50B family. | Branch migration of Holliday structures; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.431 |
eep | uppS | spr0242 | spr0240 | Determinant for enhanced expression of pheromone; Belongs to the peptidase M50B family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.881 |
frr | eep | spr0846 | spr0242 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Determinant for enhanced expression of pheromone; Belongs to the peptidase M50B family. | 0.508 |
frr | proS | spr0846 | spr0243 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] | 0.426 |
frr | uppS | spr0846 | spr0240 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.809 |
ispA | eep | spr1087 | spr0242 | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Determinant for enhanced expression of pheromone; Belongs to the peptidase M50B family. | 0.529 |
ispA | uppS | spr1087 | spr0240 | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.972 |
murG | bacA | spr0604 | spr0413 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | A lipid kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.695 |