node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABC-NBD-9 | spr0631 | spr0632 | spr0631 | ABC transporter ATP-binding protein - cobalt or other cation transport. | Conserved hypothetical protein. | 0.965 |
ABC-NBD-9 | spr0633 | spr0632 | spr0633 | ABC transporter ATP-binding protein - cobalt or other cation transport. | Conserved hypothetical protein. | 0.982 |
ABC-NBD-9 | spr0635 | spr0632 | spr0635 | ABC transporter ATP-binding protein - cobalt or other cation transport. | Hypothetical protein. | 0.804 |
ABC-NBD-9 | tenA | spr0632 | spr0634 | ABC transporter ATP-binding protein - cobalt or other cation transport. | Transcriptional regulator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.809 |
ABC-NBD-9 | thiE-2 | spr0632 | spr0637 | ABC transporter ATP-binding protein - cobalt or other cation transport. | Thiamine phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.805 |
ABC-NBD-9 | thiM-2 | spr0632 | spr0636 | ABC transporter ATP-binding protein - cobalt or other cation transport. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.804 |
spr0628 | tenA | spr0628 | spr0634 | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | Transcriptional regulator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.926 |
spr0628 | thiD | spr0628 | spr0638 | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | Phosphomethylpyrimidine kinase. | 0.962 |
spr0628 | thiE | spr0628 | spr0630 | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.611 |
spr0628 | thiM | spr0628 | spr0629 | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.955 |
spr0628 | thiM-2 | spr0628 | spr0636 | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.927 |
spr0631 | ABC-NBD-9 | spr0631 | spr0632 | Conserved hypothetical protein. | ABC transporter ATP-binding protein - cobalt or other cation transport. | 0.965 |
spr0631 | spr0633 | spr0631 | spr0633 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.970 |
spr0631 | spr0635 | spr0631 | spr0635 | Conserved hypothetical protein. | Hypothetical protein. | 0.816 |
spr0631 | tenA | spr0631 | spr0634 | Conserved hypothetical protein. | Transcriptional regulator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.871 |
spr0631 | thiE-2 | spr0631 | spr0637 | Conserved hypothetical protein. | Thiamine phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.802 |
spr0631 | thiM-2 | spr0631 | spr0636 | Conserved hypothetical protein. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.784 |
spr0633 | ABC-NBD-9 | spr0633 | spr0632 | Conserved hypothetical protein. | ABC transporter ATP-binding protein - cobalt or other cation transport. | 0.982 |
spr0633 | spr0631 | spr0633 | spr0631 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.970 |
spr0633 | spr0635 | spr0633 | spr0635 | Conserved hypothetical protein. | Hypothetical protein. | 0.830 |