node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
lysC | pabB | spr0374 | spr0582 | Aspartate kinase; Belongs to the aspartokinase family. | Para-aminobenzoate synthetase. | 0.595 |
lysC | trpA | spr0374 | spr1631 | Aspartate kinase; Belongs to the aspartokinase family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.496 |
lysC | trpD | spr0374 | spr1635 | Aspartate kinase; Belongs to the aspartokinase family. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.469 |
lysC | trpF | spr0374 | spr1633 | Aspartate kinase; Belongs to the aspartokinase family. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.677 |
pabB | lysC | spr0582 | spr0374 | Para-aminobenzoate synthetase. | Aspartate kinase; Belongs to the aspartokinase family. | 0.595 |
pabB | topA | spr0582 | spr1141 | Para-aminobenzoate synthetase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.403 |
pabB | trpA | spr0582 | spr1631 | Para-aminobenzoate synthetase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.988 |
pabB | trpB | spr0582 | spr1632 | Para-aminobenzoate synthetase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.964 |
pabB | trpC | spr0582 | spr1634 | Para-aminobenzoate synthetase. | Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. | 0.975 |
pabB | trpD | spr0582 | spr1635 | Para-aminobenzoate synthetase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.990 |
pabB | trpE | spr0582 | spr1637 | Para-aminobenzoate synthetase. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.877 |
pabB | trpF | spr0582 | spr1633 | Para-aminobenzoate synthetase. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.888 |
pabB | trpG | spr0582 | spr1636 | Para-aminobenzoate synthetase. | Anthranilate synthase component II (glutamine amido-transferase). | 0.999 |
spr1638 | trpA | spr1638 | spr1631 | Hypothetical protein. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.670 |
spr1638 | trpB | spr1638 | spr1632 | Hypothetical protein. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.781 |
spr1638 | trpC | spr1638 | spr1634 | Hypothetical protein. | Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. | 0.719 |
spr1638 | trpD | spr1638 | spr1635 | Hypothetical protein. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.688 |
spr1638 | trpE | spr1638 | spr1637 | Hypothetical protein. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.749 |
spr1638 | trpF | spr1638 | spr1633 | Hypothetical protein. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.666 |
spr1638 | trpG | spr1638 | spr1636 | Hypothetical protein. | Anthranilate synthase component II (glutamine amido-transferase). | 0.682 |