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pdhA pdhA pdhB pdhB pdhC pdhC pdhD pdhD SERP1077 SERP1077 SERP2325 SERP2325 SERP2324 SERP2324 lpdA lpdA SERP2327 SERP2327 pyk pyk SERP0856 SERP0856
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
pdhAPyruvate dehydrogenase complex E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (370 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase complex E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
 0.999
pdhC
Pyruvate dehydrogenase complex E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.999
pdhD
Pyruvate dehydrogenase complex E3 component, lipoamide dehydrogenase; Identified by similarity to EGAD:23102; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350.
 
 
 0.995
SERP1077
2-oxoisovalerate dehydrogenase, E1 component, beta subunit; Identified by similarity to EGAD:21712; match to protein family HMM PF02779; match to protein family HMM PF02780.
 0.995
SERP2325
Acetoin dehydrogenase, E1 component, beta subunit; Identified by similarity to SP:O34591; match to protein family HMM PF02779; match to protein family HMM PF02780.
 0.995
SERP2324
Acetoin dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to EGAD:108212; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
 
 0.988
lpdA
2-oxoisovalerate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350.
  
 
 0.968
SERP2327
Acetoin dehydrogenase, E3 component, dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350.
  
 
 0.958
pyk
Pyruvate kinase; Identified by similarity to EGAD:37614; match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
  
 
 0.937
SERP0856
Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855.
    
 0.932
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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