STRINGSTRING
SERP1077 SERP1077 SERP1076 SERP1076 SERP1078 SERP1078 lpdA lpdA pdhA pdhA SERP2326 SERP2326 pdhD pdhD SERP2327 SERP2327 SERP2324 SERP2324 pdhC pdhC pflB pflB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERP10772-oxoisovalerate dehydrogenase, E1 component, beta subunit; Identified by similarity to EGAD:21712; match to protein family HMM PF02779; match to protein family HMM PF02780. (327 aa)    
Predicted Functional Partners:
SERP1076
2-oxoisovalerate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to EGAD:13011; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
 
 0.999
SERP1078
2-oxoisovalerate dehydrogenase, E1 component, alpha subunit; Identified by similarity to EGAD:21637; match to protein family HMM PF00676.
 0.999
lpdA
2-oxoisovalerate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350.
 
 0.996
pdhA
Pyruvate dehydrogenase complex E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
 0.995
SERP2326
Acetoin dehydrogenase, E1 component, alpha subunit; Identified by similarity to SP:P27745; match to protein family HMM PF00676.
 0.995
pdhD
Pyruvate dehydrogenase complex E3 component, lipoamide dehydrogenase; Identified by similarity to EGAD:23102; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350.
 
 0.976
SERP2327
Acetoin dehydrogenase, E3 component, dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350.
  
 0.971
SERP2324
Acetoin dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to EGAD:108212; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
 
 0.964
pdhC
Pyruvate dehydrogenase complex E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.935
pflB
Formate acetyltransferase; Identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
   
 
 0.924
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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