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panB panB panC panC ACN13374.1 ACN13374.1 ACN14187.1 ACN14187.1 ilvD1 ilvD1 ilvD2 ilvD2 ilvE ilvE ACN16309.1 ACN16309.1 birA birA coaBC coaBC hisS hisS
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
panBPanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (263 aa)    
Predicted Functional Partners:
panC
PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 0.998
ACN13374.1
Putative coenzyme F420-dependent NADP oxidoreductase.
 
   
 0.940
ACN14187.1
Branched-chain amino acid aminotransferase.
    
 0.921
ilvD1
IlvD1; Dihydroxy-acid dehydratase IlvD (DAD); Belongs to the IlvD/Edd family.
     
 0.919
ilvD2
IlvD2; Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family.
     
 0.919
ilvE
IlvE; Branched-chain amino acid aminotransferase IlvE.
    
 0.914
ACN16309.1
Putative ketopantoate reductase.
    
 0.717
birA
BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.690
coaBC
CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
   
 0.603
hisS
HisS; histidyl-tRNA synthetase HisS (Histidine--tRNA ligase) (HisRS).
     
 0.600
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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