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folD folD fhs fhs purE purE glyA glyA DP1612 DP1612 fmt fmt DP1741 DP1741 DP0301 DP0301 DP1615 DP1615 DP2350 DP2350 DP0646 DP0646
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query proteins and first shell of interactors
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second shell of interactors
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Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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folDProbable methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (313 aa)    
Predicted Functional Partners:
fhs
Probable formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
 
 
 0.998
purE
Probable phosphoribosylamine--glycine ligase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family.
 
  
 0.982
glyA
Probable glycine/serine hydroxymethyltransferase (GlyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.981
DP1612
Related to 5,10-methylenetetrahydrofolate reductase.
    
 0.978
fmt
Probable methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
 
 0.973
DP1741
Related to bifunctional purine biosynthesis protein (PurH).
 
 
 0.967
DP0301
Related to glycine cleavage system, T protein; Belongs to the GcvT family.
  
 
 0.965
DP1615
Related to phosphoribosylglycinamide formyltransferase.
 
 
 0.960
DP2350
Probable formiminotransferase-cyclodeaminase.
   
 0.943
DP0646
Probable 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
    
 0.935
Your Current Organism:
Desulfotalea psychrophila
NCBI taxonomy Id: 177439
Other names: D. psychrophila LSv54, Desulfotalea psychrophila LSv54
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