STRINGSTRING
pyk pyk eno eno PAE1610 PAE1610 PAE1688 PAE1688 rpl23 rpl23 PAE2646 PAE2646 PAE2644 PAE2644 PAE1040 PAE1040 rpl6 rpl6 PAE3279 PAE3279 PAE0938 PAE0938
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pykPyruvate kinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the pyruvate kinase family. (461 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.993
PAE1610
Glucose-6-phosphate isomerase, conjectural; Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency.
  
 
 0.973
PAE1688
Malate oxidoreductase (mae); Energy metabolism; Other.
  
 0.949
rpl23
Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
 
 
 0.931
PAE2646
Pyruvate dehydrogenase E1 beta subunit; Energy metabolism; Glycolysis/gluconeogenesis.
  
 
 0.931
PAE2644
Pyruvate dehydrogenase E1 alpha subunit; Energy metabolism; Glycolysis/gluconeogenesis.
  
 
 0.930
PAE1040
Pyruvate ferredoxin oxidoreductase gamma subunit (porG); Energy metabolism; Fermentation.
   
 0.929
rpl6
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
 
   0.929
PAE3279
2-ketoacid ferredoxin oxidoreductase gamma subunit; Energy metabolism; Fermentation.
   
 0.929
PAE0938
2-oxoacid ferredoxin oxidoreductase beta subunit; Energy metabolism; Electron transport.
  
 0.928
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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