STRINGSTRING
endA endA PAE0789 PAE0789 PAE2268 PAE2268 dnaG dnaG PAE2266 PAE2266 PAE2242 PAE2242 PAE1446 PAE1446 PAE0841 PAE0841 PAE2265 PAE2265 nusA nusA trpS trpS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
endAtRNA intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (183 aa)    
Predicted Functional Partners:
PAE0789
Hypothetical protein.
    
 
 0.915
PAE2268
Protein synthesis; tRNA and rRNA base modification.
       0.847
dnaG
Conserved protein (toprim domain); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
 
   0.746
PAE2266
glycyl-tRNA synthetase; Protein synthesis; tRNA aminoacylation.
  
    0.744
PAE2242
Conserved hypothetical protein.
  
 
 0.646
PAE1446
Conserved hypothetical protein.
  
     0.625
PAE0841
Conserved hypothetical protein.
    
 0.586
PAE2265
paREP2a; Hypothetical; Conserved within genome.
       0.579
nusA
Transcription termination factor NusA, putative; Participates in transcription termination. Belongs to the NusA family.
  
     0.562
trpS
tryptophanyl-tRNA synthetase; Protein synthesis; tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
   
 0.557
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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