STRINGSTRING
PF1790 PF1790 PF1791 PF1791 PF1792 PF1792 shyB shyB trmB trmB PF0071 PF0071 PF1789 PF1789 PF0497 PF0497 PF0070 PF0070 PF0687 PF0687 PF0468 PF0468
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF1790Transcriptional regulatory protein arsR family; Function Code: 10.0 Regulatory functions: regulatory functions. (202 aa)    
Predicted Functional Partners:
PF1791
Small nucleolar rnp gar1-like protein; Function Code: 12.3 Transcription: RNA Processing.
 
     0.801
PF1792
5'-cyclic-nucleotide phosphodiesterase cpda homolog; Function Code: 10.0 Regulatory functions: regulatory functions.
       0.691
shyB
H-II hydrogenase subunit beta; Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity. May play a role in hydrogen cycling during fermentative growth. Activity exhibited with NAD in addition to NADPH. The beta and gamma subunits form the sulfur-reducing component that catalyzes the cytoplasmic production of hydrogen sulfide in the presence of elemental sulfur.
      
 0.600
trmB
Hypothetical protein; Inhibits transcription of the trehalose/maltose transport gene cluster (malE operon) and of the maltodextrin transport gene cluster (mdxE operon). Acts by binding to two different operator sequences in both promoters, preventing polymerase recruitment and transcription; Belongs to the transcriptional regulator TrmB family.
  
   
 0.582
PF0071
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
  
     0.556
PF1789
Hydrolase related to 2-haloalkanoic acid dehalogenase; Function Code: 16.0 Unknown.
       0.553
PF0497
Function Code: 16.4 Hypothetical.
      
 0.524
PF0070
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
  
     0.515
PF0687
Function Code: 12.2 Transcription: Transcription factors; (TFIIB).
  
   
 0.506
PF0468
Hypothetical protein; Function Code: 16.1 Conserved Hypothetical.
  
     0.504
Your Current Organism:
Pyrococcus furiosus
NCBI taxonomy Id: 186497
Other names: P. furiosus DSM 3638, Pyrococcus furiosus DSM 3638, Pyrococcus furiosus str. DSM 3638, Pyrococcus furiosus strain DSM 3638
Server load: low (26%) [HD]