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fumC fumC sdhA sdhA LA_1896 LA_1896 mdh mdh sfcA sfcA gltA gltA gltA-2 gltA-2 LA_1898 LA_1898 sucD sucD nadB nadB argH argH
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase flavoprotein subunit.
 
 0.988
LA_1896
Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.
  
 0.974
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.972
sfcA
Malic enzyme.
  
 
 0.967
gltA
Citrate synthase; Belongs to the citrate synthase family.
   
 0.910
gltA-2
Citrate synthase; Belongs to the citrate synthase family.
   
 0.910
LA_1898
Succinate:quinone oxidoreductase (SQR)-like protein.
     
  0.900
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.876
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
      0.827
argH
Argininosuccinate lyase.
   
 
0.826
Your Current Organism:
Leptospira interrogans
NCBI taxonomy Id: 189518
Other names: L. interrogans serovar Lai str. 56601, Leptospira interrogans serovar Lai str. 56601
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