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Mkms_4647 Mkms_4647 purC purC clpP-2 clpP-2 Mkms_4993 Mkms_4993 Mkms_4645 Mkms_4645 Mkms_1431 Mkms_1431 Mkms_4649 Mkms_4649 Mkms_4646 Mkms_4646 clpP clpP Mkms_4644 Mkms_4644 Mkms_0084 Mkms_0084
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Mkms_4647Oligopeptidase B, Serine peptidase, MEROPS family S09A; PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: mmc:Mmcs_4559 oligopeptidase B. (706 aa)    
Predicted Functional Partners:
purC
KEGG: mmc:Mmcs_4560 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase.
       0.874
clpP-2
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.864
Mkms_4993
Conserved hypothetical protein 103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.775
Mkms_4645
PFAM: glutathione peroxidase; KEGG: mmc:Mmcs_4557 glutathione peroxidase; Belongs to the glutathione peroxidase family.
     
 0.704
Mkms_1431
KEGG: mmc:Mmcs_1413 hypothetical protein.
   
  
 0.688
Mkms_4649
KEGG: mmc:Mmcs_4561 putative conserved transmembrane protein.
       0.688
Mkms_4646
PFAM: regulatory protein, TetR; KEGG: mmc:Mmcs_4558 transcriptional regulator, TetR family.
       0.686
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.683
Mkms_4644
KEGG: mmc:Mmcs_4556 hypothetical protein.
       0.591
Mkms_0084
Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family.
  
  
 0.450
Your Current Organism:
Mycobacterium sp. KMS
NCBI taxonomy Id: 189918
Other names: M. sp. KMS
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