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dcd_1 dcd_1 pyrG pyrG ndk ndk nrdD nrdD dcd_2 dcd_2 MK0292 MK0292 pyrE pyrE frdB/glpC frdB/glpC
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dcd_1Deoxycytidine deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (193 aa)    
Predicted Functional Partners:
pyrG
CTP synthase (UTP-ammonia lyase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 
 0.939
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
 
 0.938
nrdD
Oxygen-sensitive ribonucleoside-triphosphate reductase.
    
 0.914
dcd_2
Deoxycytidine deaminase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
  
  
 
0.906
MK0292
Predicted phosphohydrolase.
     
 0.638
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.478
frdB/glpC
Succinate dehydrogenase/fumarate reductase Fe-S protein.
  
    0.441
Your Current Organism:
Methanopyrus kandleri
NCBI taxonomy Id: 190192
Other names: M. kandleri AV19, Methanopyrus kandleri AV19, Methanopyrus kandleri str. AV19
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