STRINGSTRING
CC_3610 CC_3610 dnaN dnaN CC_3644 CC_3644 ligA ligA polA polA CC_1823 CC_1823 CC_2041 CC_2041 imuB imuB CC_2040 CC_2040 CC_2011 CC_2011 CC_3706 CC_3706
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC_3610DNA ligase, ATP-dependent, putative; Identified by match to protein family HMM. (541 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.993
CC_3644
Conserved hypothetical protein; Identified by Glimmer2; putative.
 0.988
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
    
 0.981
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.934
CC_1823
DNA polymerase III, delta prime subunit; Identified by match to protein family HMM.
   
 0.878
CC_2041
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.822
imuB
Hypothetical protein; Along with DnaE2 and ImuA is required for the error-prone processing of DNA lesions.
  
 
 0.814
CC_2040
ATP-dependent RNA helicase, DEAD/DEAH family; Identified by match to protein family HMM.
 
    0.804
CC_2011
Exodeoxyribonuclease III; Identified by match to TIGR protein family HMM TIGR00195.
  
 
 0.722
CC_3706
Exodeoxyribonuclease III; Identified by match to TIGR protein family HMM TIGR00195.
  
 
 0.722
Your Current Organism:
Caulobacter vibrioides CB15
NCBI taxonomy Id: 190650
Other names: C. vibrioides CB15, Caulobacter crescentus CB15, Caulobacter vibrioides ATCC 19089
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.