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gmk gmk guaA guaA adk adk rpoZ rpoZ Cj0834c Cj0834c argS argS Cj1386 Cj1386 eno eno tatA tatA ndk ndk dnaK dnaK
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
 
 0.972
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
 0.966
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
  
  
 0.959
Cj0834c
Original (2000) note: Cj0834c, possible periplasmic protein, len: 412 aa; similar in C-terminus to ankyrin repeat-containing proteins e.g. ANKH_CHRVI ankyrin homolog precursor (323 aa), fasta scores; opt: 194 z-score: 229.9 E(): 1.7e-05, 28.9% identity in 194 aa overlap. No Hp match. Some similarity to ankyrin repeats in Cj1386 (29.3% identity in 99 aa overlap). Contains 2x Pfam match to entry PF00023 ank, Ank repeat, and possible N-terminal signal sequence; Updated (2006) note: No specific characterisation with acceptable identity scores carried out yet. Putative kept within product f [...]
  
 0.929
argS
arginyl-tRNA synthetase; Original (2000) note: Cj1175c, argS, arginyl-tRNA synthetase, len: 530 aa; similar to many e.g. SYR_BACSU arginyl-tRNA synthetase (EC 6.1.1.19) (556 aa), fasta scores; opt: 1206 z-score: 1360.5 E(): 0, 38.2% identity in 529 aa overlap. 51.1% identity to HP0319. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature, and Pfam match to entry PF00750 tRNA-synt_1d,tRNA synthetases class I (R); Updated (2006) note: Characterised in Bacillus subtilis with acceptable identity score. Putative not added to product function. Functional classification -Amin [...]
  
  
 0.921
Cj1386
Original (2000) note: Cj1386, ankyrin-repeat containing protein, len: 412 aa; similar to proteins downstream of catalase in Pseudomonads e.g. TR:P95546 (EMBL:U16026) Pseudomonas syringae ANKF precursor (183 aa), fasta scores; opt: 217 z-score: 286.8 E(): 1.2e-08,31.3% identity in 134 aa overlap, and to eukaryotic ankyrin proteins e.g. ANK1_MOUSE ankyrin (1862 aa), fasta scores; opt: 181 z-score: 226.3 E(): 2.8e-05, 29.1% identity in 117 aa overlap. No Hp match. Also similar to Cj0834c (29.3% identity in 99 aa overlap). Contains 2x Pfam match to entry PF00023 ank, Ank repeat; Updated (2 [...]
    
 0.918
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.917
tatA
Sec-independent protein translocase (TatA/E homolog); Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
  
  
 0.893
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.862
dnaK
Heat shock protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.860
Your Current Organism:
Campylobacter jejuni NCTC 11168
NCBI taxonomy Id: 192222
Other names: C. jejuni subsp. jejuni NCTC 11168 = ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819, Campylobacter jejuni subsp. jejuni ATCC 700819 = NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168, Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
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