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acs acs leuA-1 leuA-1 CT1088 CT1088 leuA-2 leuA-2 nifJ nifJ gltA gltA aldA aldA CT0163 CT0163 ackA ackA accC accC nifV nifV
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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acsacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (621 aa)    
Predicted Functional Partners:
leuA-1
2-isopropylmalate synthase; Identified by similarity to EGAD:32071; match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.977
CT1088
Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629.
  
 0.975
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.963
nifJ
Pyruvate flavodoxin/ferrodoxin oxidoreductase; Identified by similarity to EGAD:9985; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM PF02775; match to protein family HMM TIGR02176.
  
 
 0.962
gltA
Citrate synthase; Identified by similarity to EGAD:20399; similarity to EGAD:77210; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family.
  
 0.959
aldA
Aldehyde dehydrogenase; Identified by similarity to EGAD:4728; match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
  
 0.944
CT0163
Alpha oxoglutarate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:144640; match to protein family HMM PF01558; match to protein family HMM PF01855.
  
 
 0.943
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.926
accC
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.923
nifV
Homocitrate synthase; Identified by similarity to EGAD:10481; match to protein family HMM PF00682; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.917
Your Current Organism:
Chlorobaculum tepidum
NCBI taxonomy Id: 194439
Other names: C. tepidum TLS, Chlorobaculum tepidum TLS, Chlorobium tepidum TLS
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