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hemA2 hemA2 hemL hemL Noca_3921 Noca_3921 hemC hemC gltX gltX hemA1 hemA1 Noca_0496 Noca_0496 Noca_0497 Noca_0497 Noca_2600 Noca_2600 Noca_1958 Noca_1958 Noca_1957 Noca_1957
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query proteins and first shell of interactors
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second shell of interactors
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filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hemA2glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (448 aa)    
Predicted Functional Partners:
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: sma:SAV4795 putative glutamate-1-semialdehyde 2,1-aminotransferase.
 
 0.988
Noca_3921
PFAM: aminotransferase class-III; KEGG: pae:PA5523 glutamate-1-semialdehyde 2,1-aminomutase, putative; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.973
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.956
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
     
 0.941
hemA1
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
  
 
0.926
Noca_0496
uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO3317 putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase.
 
  
 0.910
Noca_0497
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sma:SAV4742 putative 5-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.905
Noca_2600
TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6796 uroporphyrin-III C-methyltransferase / precorrin-2 oxidase / ferrochelatase.
 
  
 0.859
Noca_1958
PFAM: cytochrome c assembly protein; KEGG: mxa:MXAN_3253 cytochrome c-type biogenesis protein CcmF.
     
 0.793
Noca_1957
CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
     
 0.787
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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