node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apt | gmk | cg1862 | cg1810 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PROBABLE GUANYLATE KINASE PROTEIN; Essential for recycling GMP and indirectly, cGMP. | 0.989 |
apt | guaA | cg1862 | cg0703 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PUTATIVE GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | 0.993 |
apt | hpt | cg1862 | cg2985 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.984 |
apt | prsA | cg1862 | cg1075 | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE ISOZYME 2 PR; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.446 |
gmk | apt | cg1810 | cg1862 | PROBABLE GUANYLATE KINASE PROTEIN; Essential for recycling GMP and indirectly, cGMP. | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.989 |
gmk | guaA | cg1810 | cg0703 | PROBABLE GUANYLATE KINASE PROTEIN; Essential for recycling GMP and indirectly, cGMP. | PUTATIVE GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | 0.994 |
gmk | hpt | cg1810 | cg2985 | PROBABLE GUANYLATE KINASE PROTEIN; Essential for recycling GMP and indirectly, cGMP. | HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.971 |
gmk | ihf | cg1810 | cg1811 | PROBABLE GUANYLATE KINASE PROTEIN; Essential for recycling GMP and indirectly, cGMP. | Putative integration host factor cIHF. | 0.920 |
gmk | lepA | cg1810 | cg2571 | PROBABLE GUANYLATE KINASE PROTEIN; Essential for recycling GMP and indirectly, cGMP. | Membrane GTPase LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.953 |
gmk | ndk | cg1810 | cg2603 | PROBABLE GUANYLATE KINASE PROTEIN; Essential for recycling GMP and indirectly, cGMP. | NUCLEOSIDE DIPHOSPHATE KINASE; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.927 |
gmk | prsA | cg1810 | cg1075 | PROBABLE GUANYLATE KINASE PROTEIN; Essential for recycling GMP and indirectly, cGMP. | PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE ISOZYME 2 PR; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.921 |
gmk | pyk | cg1810 | cg2291 | PROBABLE GUANYLATE KINASE PROTEIN; Essential for recycling GMP and indirectly, cGMP. | PYRUVATE KINASE. | 0.929 |
gmk | rpoZ | cg1810 | cg1809 | PROBABLE GUANYLATE KINASE PROTEIN; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit K/omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.969 |
gmk | tpi | cg1810 | cg1789 | PROBABLE GUANYLATE KINASE PROTEIN; Essential for recycling GMP and indirectly, cGMP. | TRIOSEPHOSPHATE ISOMERASE; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.932 |
guaA | apt | cg0703 | cg1862 | PUTATIVE GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.993 |
guaA | gmk | cg0703 | cg1810 | PUTATIVE GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | PROBABLE GUANYLATE KINASE PROTEIN; Essential for recycling GMP and indirectly, cGMP. | 0.994 |
guaA | hpt | cg0703 | cg2985 | PUTATIVE GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.982 |
guaA | ihf | cg0703 | cg1811 | PUTATIVE GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | Putative integration host factor cIHF. | 0.574 |
guaA | lepA | cg0703 | cg2571 | PUTATIVE GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | Membrane GTPase LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.889 |
guaA | ndk | cg0703 | cg2603 | PUTATIVE GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP. | NUCLEOSIDE DIPHOSPHATE KINASE; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.601 |