STRINGSTRING
cobS cobS cobU cobU cobT cobT Cgl2236 Cgl2236 pduO pduO cobL cobL Cgl2198 Cgl2198 cobA cobA Cgl1534 Cgl1534 hemD hemD bioD bioD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
cobSPUTATIVE COBALAMIN (5'-PHOSPHATE) SYNTHASE; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (307 aa)    
Predicted Functional Partners:
cobU
COBINAMIDE KINASE / COBINAMIDE PHOSPHATE GUANYLYLTRANSFERASE.
 
 
 0.998
cobT
PROBABLE NICOTINATE-NUCLEOTIDE-- DIMETHYLBENZIMIDAZOLEPHOSPHORIBOSYLTRANSFERASE PROTEIN; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
  
 0.991
Cgl2236
Ribonuclease HI.
 
 
 0.954
pduO
ADENOSYLCOBALAMIN-DEPENDENT DIOL DEHYDRATASE GAMMA; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.944
cobL
PRECORRIN-6Y C5,15-METHYLTRANSFERASE (DECARBOXYLATING).
 
  
 0.941
Cgl2198
Putative membrane protein.
  
    0.756
cobA
UROPORPHYRINOGEN III SYNTHASE/METHYLTRANSFERASE; Belongs to the precorrin methyltransferase family.
 
   
 0.735
Cgl1534
Membrane protein implicated in regulation of membrane protease activity.
   
    0.726
hemD
UROPORPHYRINOGEN III SYNTHASE/METHYLTRANSFERASE.
 
   
 0.718
bioD
DETHIOBIOTIN SYNTHETASE PROTEIN; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
  
 0.713
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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