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ribE ribE ribD ribD ribH ribH ribB ribB ribA ribA ribF ribF yigB yigB ubiB ubiB hpaC hpaC ybjI ybjI appA appA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Predicted Interactions
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textmining
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protein homology
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ribERiboflavin synthase, alpha chain; Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil. (213 aa)    
Predicted Functional Partners:
ribD
Bifunctional pyrimidine deaminase/reductase; Code: H; COG: COG1985.
  
 0.999
ribH
Riboflavin synthase, beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
 
 0.998
ribB
3,4 dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
  
 0.997
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
 
 0.995
ribF
Putative regulator; Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
  
 
 0.938
yigB
Putative phosphatase; Catalyzes the dephosphorylation of flavin mononucleotide (FMN); Belongs to the HAD-like hydrolase superfamily.
   
 
  0.901
ubiB
Ferrisiderophore reductase, flavin reductase (NADPH:flavin oxidoreductase); Code: HC; COG: COG0543.
    
  0.901
hpaC
Component C of the 4HPA-hydroxylase; Code: R; COG: COG1853.
    
  0.901
ybjI
Conserved hypothetical protein; Code: R; COG: COG0561.
     
  0.900
appA
Phosphoanhydride phosphorylase; pH 2.5 acid phosphatase.
     
  0.900
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
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